Incidence and survival of laryngeal cancer in Denmark: a nation-wide study from 1980 to 2014

Incidence and survival of laryngeal cancer in Denmark: a nation-wide study from 1980 to 2014
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DOI:
10.1080/0284186x.2019.1572923
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发表时间:
2019-07-03
期刊:
影响因子:
3.1
通讯作者:
von Buchwald, Christian
von Buchwald, Christian
中科院分区:
医学3区
文献类型:
--
作者:
Nahavandipour, Arvin;Jakobsen, Kathrine Kronberg;von Buchwald, Christian

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背景资料:本登记研究的目的是评估1980年至2014年丹麦人群喉癌发病率和生存率的趋势。方法:本研究包括1980年至2014年期间在丹麦癌症登记处(DCR)登记的所有喉癌患者。计算每10万人的年龄调整发病率(AAIR)和平均年变化百分比(AAPC)。我们评估了性别、解剖位置、诊断年份和组织学类型与5年相对生存率的关系。结果:共纳入8748例患者(82%为男性)。诊断时的中位年龄为60岁,范围为18-101岁。AAIR从1980年的3.6/100,000下降到2014年的2.3/100,000,AAPC为-0.8%(p
Background: The purpose of this registry study was to evaluate trends in incidence and survival of laryngeal cancer in the Danish population from 1980 to 2014.Methods: This study includes all patients with laryngeal cancer registered in the Danish Cancer Registry (DCR) in the period 1980-2014. The age-adjusted incidence rate (AAIR) per 100,000 and average annual percent change (AAPC) were calculated. We evaluated the relative survival at five years in relation to gender, anatomical location, year at diagnosis, and histological type. Further, an age-period-cohort (APC) model of incidence was constructed.Results: A total of 8748 patients (82% males) were included. The median age at diagnosis was 60 years, range 18-101 years. The AAIR decreased from 3.6 per 100,000 in 1980 to 2.3 per 100,000 in 2014 with an AAPC of -0.8% (p