Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones
Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones
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DOI：
10.1039/b107612b
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发表时间：
2001-12
期刊：
影响因子：
9.8
通讯作者：
V. R. Rani;N. Srinivas;M. R. Kishan;S. J. Kulkarni;K. Raghavan
中科院分区：
文献类型：
--
作者：
V. R. Rani;N. Srinivas;M. R. Kishan;S. J. Kulkarni;K. Raghavan
报道了一种沸石催化的环境友好的一步合成二氢嘧啶酮类化合物的方法。与经典的Biginelli反应相比，催化剂的可重复使用性和纯产物的易于分离、选择性和高产率是该方法的一些独特特征。
A zeolite catalyzed, single step and environmentally friendly process for the synthesis of dihydropyrimidinones, a pharmacologically important class of compounds, is reported. Reusability of the catalyst and the ease of separation of pure product, selectively and in high yields in comparison to the classical Biginelli reaction, are a few of the unique features of this process.