Location of the corticospinal tract in the internal capsule at MR imaging.
Location of the corticospinal tract in the internal capsule at MR imaging.
复制标题
磁共振成像中皮质脊髓束在内囊中的位置。
DOI：
10.1148/radiology.191.2.8153321
复制
发表时间：
1994
期刊：
影响因子：
19.7
通讯作者：
A. Hirano
中科院分区：
文献类型：
--
作者：
A. Yagishita;I. Nakano;M. Oda;A. Hirano
目的
检查T2加权磁共振（MR）图像上后内囊（IC）内的高信号灶是否代表皮质脊髓束（CST）的纤维。
材料和方法
作者回顾了100例对照组和35例肌萎缩侧索硬化（ALS）患者的MR图像，以及7例对照组和5例ALS患者的脑标本。
结果
在后IC中，来自对照受试者的脑标本显示出具有大轴突和厚髓鞘的苍白区域。在5例ALS患者中，脑标本显示同一区域的CST变性。35例ALS患者中有5例MRI表现为CST变性的异常高信号。在同一区域，在对照组中发现高信号灶。
结论
IC中的正常高信号灶代表CST的纤维。髓鞘厚的大纤维的存在可能在这些信号强度变化中起重要作用。
PURPOSE
To examine whether hyperintense foci in the posterior internal capsule (IC) on T2-weighted magnetic resonance (MR) images represent fibers of the corticospinal tract (CST).
MATERIALS AND METHODS
The authors reviewed MR images of 100 control subjects and 35 patients with amyotrophic lateral sclerosis (ALS) and brain specimens from seven control subjects and five ALS patients.
RESULTS
In the posterior IC, the brain specimens from control subjects demonstrated a pale area with large axons and thick myelin sheaths. In five ALS patients, the brain specimens showed degeneration of the CST in the same region. MR images demonstrated abnormal hyperintensity that represented degeneration of the CST in five of 35 ALS patients. In the same region, hyperintense foci were found in the control subjects.
CONCLUSION
Normal hyperintense foci in the IC represent the fibers of the CST. The presence of large fibers with thick myelin sheaths may play an important role in these signal intensity variations.