Necrotizing retinitis induced by Angiostrongylus cantonensis
Necrotizing retinitis induced by Angiostrongylus cantonensis
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DOI：
10.1016/j.ajo.2005.09.033
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发表时间：
2006-03-01
影响因子：
4.2
通讯作者：
Cho, WL
中科院分区：
文献类型：
--
作者：
Liu, IH;Chung, YM;Cho, WL
目得：描述一例由广州管圆线虫引起的双侧坏死性视网膜炎。设计：干预性病例报告。方法：一名52岁的亚洲妇女在吃了几个未煮熟的蜗牛后发生嗜酸性粒细胞性脑膜炎。一周后，双眼突然出现视力丧失。结果：血清和脑脊液酶联免疫吸附试验阳性，视网膜下液免疫印迹试验阳性，证实广州管圆线虫感染。经甲苯咪唑、左旋咪唑及皮质类固醇治疗后，这些坏死斑块逐渐消退。结论：广州管圆线虫感染是坏死性视网膜炎的病因之一。
PURPOSE: To describe a case of bilateral necrotizing retinitis induced by Angiostrongylus cantonensis.DESIGN: Interventional case report.METHODS: A 52-year-old Asian woman developed eosinophilic meningitis after eating several undercooked snails. One week later, sudden onset of vision loss was noted in both eyes. Widespread yellow retinal exudates were accompanied by bullous retinal detachment in both eyes.RESULTS: Angiostrongylus cantonensis infection was con, firmed by positive enzyme,linked immunosorbent assay of the serum and cerebrospinal fluid, and a positive Western blot test of the subretinal fluid. After treatment with mebendazole, levamisole, and corticosteroid, these necrotizing patches regressed gradually. However, the final visual acuity was no light perception.CONCLUSIONS: Angiostrongylus cantonensis infection should be considered as one of the causes of necrotizing retinitis.