Stepwise evolution of the structure and electronic properties of DNA.
Stepwise evolution of the structure and electronic properties of DNA.
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DNA 结构和电子特性的逐步演化。
DOI：
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发表时间：
2003
影响因子：
15
通讯作者：
X. Zuo
中科院分区：
文献类型：
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作者：
F. Lewis;Xiaoyang Liu;Yansheng Wu;X. Zuo
本文研究了一类具有1 ~ 11个A：T碱基对的双链DNA偶联物的光学性质。需要少至2至4个碱基来建立类似于较长寡聚物的碱基对吸收和圆二色性光谱。二苯乙烯发色团表现出激子耦合圆二色性，甚至可以观察到11个插入碱基对，距离约。40埃的这些光谱的符号和振幅的依赖性揭示了B-DNA作为螺旋标尺的能力。
The optical properties of a family of duplex DNA conjugates possessing from 1 to 11 A:T base pairs and covalently attached stilbene chromophores at both ends have been investigated. As few as from two to four base bairs are needed to establish base-pair absorption and circular dichroism spectra similar to those of longer oligomers. The stilbene chromophores exhibit exciton-coupled circular dichroism, which can be observed even with 11 intervening base pairs, a distance of ca. 40 A. The dependence of the sign and amplitude of these spectra reveals the ability of B-DNA to serve as a helical ruler.