Evaluation of Shoulder Disorders by 2-[F-18]-fluoro-2-deoxy-D-glucose Positron Emission Tomography and Computed Tomography
Evaluation of Shoulder Disorders by 2-[F-18]-fluoro-2-deoxy-D-glucose Positron Emission Tomography and Computed Tomography
复制标题
通过 2-[F-18]-氟-2-脱氧-D-葡萄糖正电子发射断层扫描和计算机断层扫描评估肩部疾病
DOI：
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发表时间：
2010
影响因子：
2.5
通讯作者：
Venkat Gorthi
中科院分区：
文献类型：
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作者：
Young Lae Moon;Sang Hong Lee;Sung Yong Park;Jae Cheol Yu;Venkat Gorthi
背景：虽然氟-18-氟脱氧葡萄糖(FDG)正电子发射断层扫描(PET)在定位解剖结构方面存在局限性，但将其与计算机断层扫描(CT)相结合使其更有效地克服了这些局限性。本研究旨在评价正电子发射计算机断层扫描(PET/CT)对肩部疾病的诊断价值。方法对25例接受FDG-PET/CT扫描的患者进行回顾性分析。所有患者的年龄都在60岁以上，他们都接受了肩部疼痛的临床和放射学评估。研究时间为2006年5月至2008年5月。其中一名患者的肩膀有转移灶，这名患者被排除在研究之外，因此研究对象的总数最终为24名患者。结果PET/CT诊断肩痛的敏感性为67%，特异性为73%，阳性预测值为60%，阴性预测值为79%，假阳性率为27%，假阴性率为33%。经手术治疗成功的4例(肩袖撕裂3例，撞击综合征1例)，PET/CT均为阴性。6例保守治疗后疼痛消退(RCT 1例，可疑RCT 2例，撞击综合征3例)均为阴性。所有骨关节炎和类风湿关节炎患者的PET/CT扫描均为阳性。结论PET/CT是现有影像手段的有益补充，可在早期评估肿瘤的功能和病理生理过程，可帮助医生更好地作出术前和术后的治疗决策。
Background Although flourine-18-flourodeoxyglucose (FDG) positron emission tomography (PET) has a limitation for localizing anatomical structures, combining it with computed tomography (CT) has made it more efficient for overcoming such limitations. This study aims to evaluate the efficacy of PET/CT for evaluating diseases of the shoulder. Methods Retrospective examination was performed on 25 patients who underwent FDG-PET/CT scanning. All the patients were over 60 years of age, and they were evaluated both clinically and radiologically for shoulder pain. The study period was from May, 2006 to May, 2008. One of the patients had metastatic lesion in a shoulder and this patient was excluded from the study, so the total number of subjects in the study was finally 24 patients. Results PET/CT showed 67% sensitivity, 73% specificity, a positive predictive value of 60%, a negative predictive value of 79%, 27% false positivity and 33% false negativity concerning shoulder pain. PET/CT showed negative finding in 4 cases that were successfully treated by operative treatment (rotator cuff tear [RCT], 3 cases; impingement syndrome, 1 case). Negative findings were also noted in 6 cases in which the pain subsided after conservative treatment (RCT, 1 case; suspected RCT, 2 cases; impingement syndrome, 3 cases). All the patients with osteoarthritis and rheumatoid arthritis had positive findings on PET/CT scanning. Conclusions PET/CT is a useful adjunct to the existing imaging modalities to assess functional and pathophysiologic processes and at a very early stage, and so PET/CT can help physicians make better preoperative and postoperative decisions on treatment.