Muscle abnormalities associated with the twin reversed-arterial-perfusion (TRAP) sequence (acardia).
Muscle abnormalities associated with the twin reversed-arterial-perfusion (TRAP) sequence (acardia).
复制标题
与双反向动脉灌注 (TRAP) 序列（无心）相关的肌肉异常。
DOI：
10.1002/tera.1420300303
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Stephens,TD
中科院分区：
文献类型：
--
作者：
Stephens,TD
尽管自1533年以来，文献中已报告了超过400个贲门（双逆动脉灌注，TRAP）标本，但很少尝试对循环以外的任何东西进行详细评价。本研究的目的是根据假定的病因和发病机制、反向动脉灌注和随后的胎儿退行性变化，评价9例TRAP标本中的各种肢体缺陷。检验了两个假设：（1）形成的组织的变性不应导致组织重排，和（2）一种组织类型应优先于其它组织类型丢失。这些假设都没有得到数据的支持。替代的解释进行了讨论，以及这些意见的影响，反向动脉灌注的概念。
Even though over 400 acardia (twin reversed‐arterial‐perfusion, TRAP) specimens have been reported in the literature since 1533, few attempts have been made to provide detailed evaluation of anything other than the circulation. The purpose of this study was to evaluate the various limb defects in nine TRAP specimens in light of the presumed etiology and pathogenesis, reversed arterial perfusion, and subsequent degenerative changes in the fetus. Two hypotheses were tested: (1) degeneration of formed tissues should not result in tissue rearrangement and (2) one tissue type should be lost in preference to the others. Neither of these hypotheses were supported by the data. Alternative explanations are discussed as well as the implications of these observations on the concept of reversed arterial perfusion.