Longitudinal Study (32 Years) of Exercise Tolerance, Breathing Response, Blood Pressure, and Blood Lipids in Young Men
Longitudinal Study (32 Years) of Exercise Tolerance, Breathing Response, Blood Pressure, and Blood Lipids in Young Men
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年轻男性运动耐量、呼吸反应、血压和血脂的纵向研究（32 年）
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
H. Blackburn
中科院分区：
文献类型：
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作者：
R. Gillum;H. Taylor;JosephT. Anderson;H. Blackburn
Changes In exercise tolerance, blood lipids, and blood pressure from youth to middle age was studied In 106 subjects followed 32 years. In addition, the responses to cold pressor and CO2 stress were studied as correlates of future lipids and blood pressure. Treadmill exercise test, cold pressor test, response to breathing a mixture of 6% CO2 and 21% O2 for 5 minutes, blood pressure, and lipid measurements were performed in 1947 when subjects were 20 ± 2 years old. Exercise, blood pressure and lipid tests were repeated in 1979. Tracking of blood pressure and pulse response to exercise over the period was demonstrated. Baseline exercise response correlated with future blood pressure, cholesterol, trlglycerldes, and high density lipoproteins. Change In exercise pulse rate over the period correlated with change in cholesterol. Cold pressor systolic blood pressure response correlated with future systolic blood pressure and trlglycerldes. Pulse and blood pressure response to CO, breathing correlated with cholesterol, trlglyceride and high density lipoprotein 32 years later. These correlations were Independent of baseline values of the varlables and body mass Index. Individuals who were judged “fit” (exercise pulse rise < median) at both baseline and follow-up had the best cardiovascular risk profile (blood pressure and lipids). Blood pressure and pulse response to exercise tracked between ages 20 and 50. Exercise, cold pressor, and CO, responses In youth correlated with blood lipid levels In middle age. (Arteriosclerosis 1:455-462, November/December 1981)
