ESTIMATING THE LIKELIHOOD OF SIGNIFICANT CORONARY-ARTERY DISEASE
ESTIMATING THE LIKELIHOOD OF SIGNIFICANT CORONARY-ARTERY DISEASE
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DOI：
10.1016/0002-9343(83)90406-0
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发表时间：
1983-01-01
影响因子：
5.9
通讯作者：
ROSATI, RA
中科院分区：
文献类型：
--
作者：
PRYOR, DB;HARRELL, FE;ROSATI, RA
在 1969 年至 1979 年间连续检查了 3627 名有症状、转诊接受心导管检查的患者的 23 项临床特征中，发现 9 项对于估计患者患有严重冠状动脉疾病的可能性非常重要。使用这些特征的模型前瞻性地应用于 1979 年以来转诊的 1811 名患者，并用于估计文献中报告的亚组中的疾病患病率，可以准确估计疾病的可能性。由于基于临床特征对重大疾病可能性的准确估计是可重复的，因此它们应该用于解释额外的无创测试的结果和量化附加的诊断价值。
Among 23 clinical characteristics examined in 3627 consecutive, symptomatic patients referred for cardiac catheterization between 1969 and 1979, 9 were found to be important for estimating the likelihood a patient had of significant coronary artery disease. A model using these characteristics accurately estimated the likelihood of disease when applied prospectively to 1811 patients referred since 1979, and when used to estimate the prevalence of disease in subgroups reported in the literature. Since accurate estimates of the likelihood of significant disease that are based on clinical characteristics are reproducible, they should be used in interpreting the results of additional noninvasive tests and in quantitating the added diagnostic value.