Carbon Nanotubes as Electrical Interfaces with Neurons
Carbon Nanotubes as Electrical Interfaces with Neurons
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DOI：
10.1007/978-90-481-8553-5_11
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发表时间：
2010-01-01
期刊：
影响因子：
--
通讯作者：
Parpura, Vladimir
中科院分区：
文献类型：
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作者：
Lee, William;Parpura, Vladimir
碳纳米管（CNTs）是一种新兴的生物医学应用纳米材料。由于其独特的结构、机械和电子性能。碳纳米管可以用作大脑，特别是神经元的电接口。基于CNT的神经界面/电极已被用于细胞培养和体内;它们在监测和刺激神经元活动方面提供了优于标准金属基电极的优势。大脑和机器接口的挑战之一是用于电极构造的材料的生物相容性。虽然碳纳米管似乎具有生物相容性，但迄今为止尚未设定暴露限值。在基于CNT的电极/装置可以用于人类受试者之前，需要建立用于CNT的适当的（国际）国家标准/规则。
Carbon nanotubes (CNTs) are emerging as promising nanomaterials for biomedical applications. Due to their unique structural, mechanical and electronic properties. CNTs can be used as electrical interlaces with the brain in particular with neurons. CNT-based neural interfaces/electrodes have been employed in cell culture and in vivo; they offer advantages over standard metal-based electrodes in terms of monitoring and stimulation of neuronal activity. One of the challenges for interfacing brain and machine is the biocompatibility of the materials used for electrode construction. While CNTs appear biocompatible, the exposure limits have not been set thus far. An appropriate (inter)national standards/rules for the use of CNTs need to be established before CNT-based electrodes/devices can be used in human subjects.