CMOS cascode source-drain follower for monolithically integrated biosensor array
CMOS cascode source-drain follower for monolithically integrated biosensor array
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DOI：
10.1093/ietele/e91-c.9.1505
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发表时间：
2008-09-01
影响因子：
0.5
通讯作者：
Uno, Shigeyasu
中科院分区：
文献类型：
--
作者：
Nakazato, Kazuo;Ohura, Mitsuo;Uno, Shigeyasu
设计并实现了单片集成生物传感器阵列的源漏跟随器。该电路充当电压跟随器，其中感测晶体管在固定的栅极-源极和栅极-漏极电压下操作。它工作在10 nW的功耗。采用恒定偏置和非恒定偏置的方法研究了宽摆幅共源共栅结构。恒定偏置源漏跟随器具有单元尺寸小的优点。该芯片采用1.2 μ m标准CMOS工艺制造，并在1 nW和100 μ W之间的广泛的操作范围进行了演示。由于阈值电压的变化，使用最小尺寸的晶体管，电压跟随器的精度为30 mV。除阈值电压失配外，输出误差小于10 mV。输出的温度依赖性为0.11 mV/℃。为了提高输入电压范围和精度，研究了非恒定偏置共源共栅源漏跟随器。传感器单元的设计精度为10 mV，单元尺寸为105.3 μ m × 81.4 μ m，在1.2 μ m CMOS设计规则。传感器单元的制造和显示，除了阈值电压失配的输出中的误差是小于2 mV的总电流的范围在3 nA和10 μ A之间，在30摄氏度和100摄氏度之间的温度范围。
Source-drain follower has been designed and implemented for monolithically integrated biosensor array. The circuit acts as a voltage follower, in which a sensing transistor is operated at fixed gate-source and gate-drain voltages. It operates at 10nW power dissipation. The wide-swing cascode configurations are investigated in constant and non-constant biasing methods. The constant biased cascode source-drain follower has the merit of small cell size. The chip was fabricated using 1.2 mu m standard CMOS technology, and a wide range of operation between 1nW and 100 mu W was demonstrated. The accuracy of the voltage follower was 30 mV using minimum sized transistors, due to the variation of threshold voltage. The error in the output except for the threshold voltage mismatch was less than 10 mV. The temperature dependence of the output was 0.11 mV/degrees C. To improve the input voltage range and accuracy, non-constant biased cascode source-drain follower is examined. The sensor cell is designed for 10mV accuracy and the cell size is 105.3 mu m x 81.4 mu m in 1.2 mu m CMOS design rules. The sensor cell was fabricated and showed that the error in the Output except for the threshold voltage mismatch was less than 2 mV in a range of total current between 3nA and 10 mu A and in a temperature range between 30 degrees C and 100 degrees C.