REFLEX EXCITATION OF ANTRAL MOTILITY INDUCED BY GASTRIC DISTENSION IN THE FERRET
REFLEX EXCITATION OF ANTRAL MOTILITY INDUCED BY GASTRIC DISTENSION IN THE FERRET
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DOI：
10.1113/jphysiol.1980.sp013068
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发表时间：
1980-01-01
影响因子：
5.5
通讯作者：
SCRATCHERD, T
中科院分区：
文献类型：
--
作者：
ANDREWS, PLR;GRUNDY, D;SCRATCHERD, T
在氨基甲酸乙酯麻醉下，用50 ml 0.9 NaCl以10 ml/min的速度胀胃，引起大胃收缩。引起反射所需的胃内压阈值为3.1 +-。0.5 cmH2O。切除内脏神经后反应增强，双侧颈部迷走神经切断术后反应明显减弱，说明反射的传入肢和传出肢均位于迷走神经内。用横切的胃；胼胝体的扩张引起了上颌窦的收缩，这种收缩通过迷走神经切开术消除了。在胃排空过程中，迷走神经传入神经对胃窦运动的反射激活可能起生理作用。
In the urethane anesthetized ferret gastric inflation with 50 ml 0.9 NaCl at a rate of 10 ml/min evoked large gastric contractions. The threshold of intragastric pressure required to elicit the reflex was 3.1 .+-. 0.5 cmH2O. The response was enhanced by splanchnic nerve section and markedly reduced by bilateral cervical vagotomy, indicating that both afferent and efferent limbs of the reflex were in the vagus nerves. By using a transected stomach; distension of the corpus evoked contractions of the antrum that were abolished by vagotomy. The reflex activation of antral motility by vagal afferents with receptive fields in the corpus may play a physiological role in gastric emptying.