Predictors of craving and substance use among patients with alcohol, tobacco, cannabis or opiate addictions: Commonalities and specificities across substances
Predictors of craving and substance use among patients with alcohol, tobacco, cannabis or opiate addictions: Commonalities and specificities across substances
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DOI：
10.1016/j.addbeh.2018.01.041
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发表时间：
2018-08-01
影响因子：
4.4
通讯作者：
Auriacombe, Marc
中科院分区：
文献类型：
--
作者：
Serre, Fuschia;Fatseas, Melina;Auriacombe, Marc
介绍渴望已被提出作为成瘾复发的主要贡献者，情绪对渴望和物质使用的影响已被广泛记录。然而，关于这些影响的程度可能因不同类型的物质而异的信息尚不清楚。本研究的目的是比较情绪，渴望和物质使用的四组患者开始治疗酒精，烟草，大麻，或阿片adipate addiction.Methods：生态瞬时评估（EMA）之间的前瞻性联系使用了两个星期的时间。数据分析采用分层线性模型（HLM）。结果：159名参与者被招募（67.3%男性; M = 36.7岁）。EMA评估的平均应答率为83.1%。研究结果证实了渴望强度对酒精（γ = 0.224; p = 0.018），烟草（γ = 0.133; p = 0.013）和大麻组（γ = 0.266; p = 0.019）中下一次评估时报告的物质使用的强预测作用，但不是阿片类药物（γ = 0.098; p = 0.142）。渴望强度本身是由更大的焦虑情绪预测的（伽马= 0.108; p = 0.029）和事件阴性（γ = 0.107; p = .003）在烟草患者中，大麻患者的悲伤情绪较低（γ = -0.248; p = 0.002），阿片类药物患者的事件阴性率较低（γ = -0.201; p = .002）。虽然这些结果支持在成瘾治疗中靶向渴望的好处，在这项研究中确定的物质特异性的渴望情绪风险因素可能为个性化治疗策略的发展提供重要的见解。
Introduction Craving has been proposed as a major contributor to addiction relapse and the influence of mood on craving and substance use has been extensively documented. However, information is lacking concerning the extent to which the magnitude of these effects may vary according to different types of substances. The aim of the present study was to compare the prospective links between emotions, craving and substance use in four groups of patients beginning treatment for alcohol, tobacco, cannabis, or opiate addiction.Methods: Ecological Momentary Assessment (EMA) was used over a two-week period. Data were analyzed using hierarchical linear modeling (HLM).Results: 159 participants were recruited (67.3% male; M = 36.7 years). The average response rate to the EMA assessments was 83.1%. The findings confirmed the strong predictive role of craving intensity on substance use reported at the next assessment of the day among the alcohol (gamma = 0.224; p =.018), tobacco (gamma = 0.133; p = .013) and cannabis groups (gamma = 0.266; p = .019), but not for opiates (gamma = 0.098; p = .142). Craving intensity was itself predicted by greater anxious mood (gamma = 0.108; p = 0,029) and event negativity (gamma = 0.107; p = .003) among tobacco patients, lower sad mood among cannabis patients (gamma = -0.248; p = 0,002), and lower event negativity among opiate patients (gamma = -0.201; p = .002).Conclusion: While these results support the benefit of targeting craving in addiction treatment regardless of substance type, the substance-specific emotional risk factors for craving identified in this study may provide important insights for the development of personalized treatment strategies.