Living with chemotherapy-induced peripheral neuropathy: Uncovering the symptom experience and self-management of neuropathic symptoms among cancer survivors
Living with chemotherapy-induced peripheral neuropathy: Uncovering the symptom experience and self-management of neuropathic symptoms among cancer survivors
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DOI：
10.1016/j.ejon.2018.09.003
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发表时间：
2018-10-01
影响因子：
2.8
通讯作者：
Molassiotis, Alex
中科院分区：
文献类型：
--
作者：
Chan, Choi Wan;Cheng, Huilin;Molassiotis, Alex
目的：本研究旨在揭示神经毒性的症状经验，自我采取的方法和观点，在管理化疗引起的周围神经病变（CIPN）症状的样本中国cancer survivor.Methods：定性描述性研究，探讨个人的经验。一个有目的的样本12名女性参与者经历CIPN被邀请到半结构化的采访，谁是一个更大的前瞻性观察性研究的一部分，调查CIPN的自然进展和危险因素。在NVivo中管理文本访谈数据。结果：参与者年龄41-64岁，在访谈期间报告完成六个周期化疗方案后5 - 23个月出现中度至重度神经病变症状。从定性数据中出现了四个类别，即（1）经验变为现实：CIPN症状的特征，（2）中断和感知的威胁：执行活动和恢复工作的能力，（3）重新建立至少令人满意的幸福水平，（4）管理神经性症状的观点和方法。从患者的角度来看，CIPN症状的特征导致功能和/或心理社会健康中断，用于管理症状的自助策略表明需要提供高质量的多学科支持性护理，重点是恢复功能和心理社会健康，以及增强有关症状评估和循证策略的知识，使癌症幸存者能够科普这种复杂的症状。
Purpose: The study aimed at uncovering the symptom experience of neurotoxicity, self-adopted approaches and perspectives in managing chemotherapy-induced peripheral neuropathic (CIPN) symptoms in a sample of Chinese cancer survivors.Methods: A qualitative descriptive study was used to explore individual experiences. A purposive sample of 12 female participants experiencing CIPN was invited to semi-structured interviews who were part of a larger prospective observational study investigating the natural progression and risk factors of CIPN. Textual interview data were managed in NVivo. Content analysis was used.Results: Participants were aged 41-64 years and experienced moderate to severe neuropathic symptoms from 5 to 23 months after completion of a six-cycle chemotherapy regimens at reported during the interviews. Four categories emerged from the qualitative data, namely, (1) experience come to reality: characteristics of CIPN symptoms, (2) disruptions and perceived threat: ability to perform activities and resume work, (3) re-establishing an at least satisfactory level of well-being', and (4) views of and approaches in managing neuropathic symptoms.Conclusions: The characteristics of CIPN symptoms causing disruptions in functional and/or psychosocial wellbeing from the patients' perspectives and the self-help strategies used to manage symptoms showed a need to provide quality multidisciplinary supportive care, focusing on restoring functional and psychosocial well-being, and enhancing knowledge about symptom assessment and evidence-based strategies for empowering cancer survivors to cope with this complex symptom.