Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses.
Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses.
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模拟 150 kHz 飞秒激光脉冲直接照射时人体尸体视网膜温度升高的情况。
DOI：
10.1117/1.3631788
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发表时间：
2011
影响因子：
3.5
通讯作者：
Juhasz,Tibor
中科院分区：
文献类型：
--
作者：
Sun,Hui;Hosszufalusi,Nora;Mikula,EricR;Juhasz,Tibor
我们开发了一个二维计算机模型来预测飞秒激光角膜瓣切割过程中视网膜的温度升高。模拟150 kHz iFS高级飞秒激光的典型临床设置（0.8- 1 μJ激光脉冲能量和15 s手术时间，激光波长为1053 nm），温升为0.2°C。计算的温度曲线与使用人尸体视网膜的活体实验数据吻合良好。针对不同商业飞秒激光获得的模拟结果表明，在激光原位角膜磨镶术过程中，视网膜的温度升高不足以引起损伤。
We have developed a two-dimensional computer model to predict the temperature increase of the retina during femtosecond corneal laser flap cutting. Simulating a typical clinical setting for 150-kHz iFS advanced femtosecond laser (0.8- to 1-μJ laser pulse energy and 15-s procedure time at a laser wavelength of 1053 nm), the temperature increase is 0.2°C. Calculated temperature profiles show good agreement with data obtained fromex vivoexperiments using human cadaver retina. Simulation results obtained for different commercial femtosecond lasers indicate that during the laserin situkeratomileusis procedure the temperature increase of the retina is insufficient to induce damage.