Comparison of the simplified International Index of Erectile Function (IIEF-5) in patients of erectile dysfunction with different pathophysiologies.
Comparison of the simplified International Index of Erectile Function (IIEF-5) in patients of erectile dysfunction with different pathophysiologies.
复制标题
DOI：
10.1186/1471-2490-14-52
复制
发表时间：
2014-07-05
期刊：
影响因子：
2
通讯作者：
Tang Y
中科院分区：
文献类型：
--
作者：
Tang Z;Li D;Zhang X;Yi L;Zhu X;Zeng X;Tang Y
简化的国际勃起功能指数（IIEF-5）是勃起功能障碍（艾德）的一个方便，可靠和有效的诊断工具。然而，很少有研究关注IIEF-5在不同病理生理原因的艾德患者中的作用。本研究旨在比较具有特定病理生理学的艾德患者的IIEF-5评分。分析了3，327例艾德患者（中位年龄39岁）的IIEF-5评分。艾德的主要原因是通过五家培训医院的泌尿科/男科诊所的综合诊断程序确定的。排除了不确定病理生理原因的患者。排除176例患者，纳入3151例艾德病史在0.5年至20年之间的患者。艾德的病因包括心因性（59.2%）、血管性（21.3%）、神经性（4.1%）、解剖/结构性（2.8%）、激素性（7.1%）和药物性（5.5%）。心因性艾德和器质性艾德的IIEF-5评分中位数差异有统计学意义（15（IQR 13，17）vs. 12（IQR 9.5，14.5），P < 0.001）。器质性病变组之间（P = 0.073），或动脉源性和静脉源性病变组之间（13（IQR 10.5，15.5）vs 13（IQR 11-15），P = 0.912（校正α = 0.017））的IIEF-5评分无显著差异。然而，混合血管原因患者的中位IIEF-5评分在血管源性患者中最低（11（IQR 8.5-13.5），三组评分：P = 0.003）。男性心理性艾德的IIEF-5评分高于器质性病因，但不同器质性病理生理类型的患者之间无差异。我们的数据表明，IIEF-5不是一个明确的诊断工具，以区分ED的病理生理原因。
The simplified International Index of Erectile Function (IIEF-5) is a convenient, reliable and validated diagnostic tool for erectile dysfunction (ED). However, few studies focused on IIEF-5 in ED patients with different pathophysiological causes. ,We aim to compare the IIEF-5 score among ED patients with specific pathophysiologies in this study. The IIEF-5 score of 3,327 ED patients (median age 39 years) was analyzed. The primary causes of ED were determined by comprehensive diagnostic procedures in the urology/andrology clinics in five training hospitals. Patients with uncertain pathophysiologic cause were excluded. 176 patients were excluded, 3151 patients with ED history between 0.5 year and 20 years, were enrolled. The causes of ED was classified as psychogenic (59.2%), vasoculogenic (21.3%), neurogenic (4.1%), anatomical/structural (2.8%), hormonal (7.1%) or drug-induced (5.5%). A significant difference was detected in the median IIEF-5 score between psychogenic ED and organic ED (15 (IQR 13, 17) versus 12 (IQR 9.5, 14.5), P < 0.001). There was no significant difference of IIEF-5 scores among the organic groups (P = 0.073), or between arteriogenic and venogenic groups (13 (IQR 10.5, 15.5) versus 13 (IQR 11–15), P = 0.912 (adjusted α = 0.017)). However, the median IIEF-5 score of those with a mixed vascular cause was the lowest among vasculogenic patients (11 (IQR 8.5-13.5), scores for the three groups: P = 0.003.). The IIEF-5 scores of men with psychological ED are higher than those with organic causes, but there is no difference among patients with different organic pathophysiologies. Our data indicate that IIEF-5 is not a definitive diagnostic tool to discriminate the pathophysiological causes of ED.
登录
查看更多内容
影响因子：
2.1
作者：
Blander, DS;S치nchez-Ortiz, RF;Broderick, GA
通讯作者：
Broderick, GA
影响因子：
23.4
作者：
Corona, Giovanni;Mannucci, Edoardo;Maggi, Mario
通讯作者：
Maggi, Mario
影响因子：
2.1
作者：
Rosen, RC;Riley, A;Mishra, A
通讯作者：
Mishra, A
影响因子：
23.4
作者：
Hatzimouratidis, Konstantinos;Amar, Edouard;Wespes, Eric
通讯作者：
Wespes, Eric
影响因子：
2.6
作者：
Rhoden, EL;Telöken, C;Souto, CAV
通讯作者：
Souto, CAV