Ruthenium-Catalyzed Isomerization of Terminal Olefins: Applications to Synthesis
Ruthenium-Catalyzed Isomerization of Terminal Olefins: Applications to Synthesis
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DOI：
10.1002/anie.200804617
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发表时间：
2009-01-01
影响因子：
16.6
通讯作者：
Rosa, Carla P.
中科院分区：
文献类型：
--
作者：
Donohoe, Timothy J.;O'Riordan, Timothy J. C.;Rosa, Carla P.
（化学方程式）In，out，烯烃约：衍生自Grubbs第二代复分解催化剂的氢化钌络合物已被证明是用于将末端烯烃选择性异构化为相应丙烯基衍生物的有效催化剂（参见方案）。这种方法已被应用于一些合成，使复杂的天然产品的访问。Cy=环己基，Mes=均三甲苯基，Cy =甲氧基甲基。© 2009 Wiley-VCH Verlag GmbH and Co. KGaA.
(Chemical Equation Presented) In, out, olefin about: A ruthenium hydride complex derived from the Grubbs second-generation metathesis catalyst has proven to be an efficient catalyst for the selective isomerization of terminal olefins to the corresponding propenyl derivatives (see scheme). This methodology has been applied in a number of syntheses to enable access to complex natural products. Cy=cyclohexyl, Mes=mesityl, MOM=methoxymethyl. © 2009 Wiley-VCH Verlag GmbH and Co. KGaA.