Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source.
Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source.
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DOI：
10.1364/ol.42.003193
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发表时间：
2017-08-15
期刊：
影响因子：
3.6
通讯作者：
Fujimoto JG
中科院分区：
文献类型：
--
作者：
Liang K;Ahsen OO;Wang Z;Lee HC;Liang W;Potsaid BM;Tsai TH;Giacomelli MG;Jayaraman V;Mashimo H;Li X;Fujimoto JG
内窥镜光学相干断层扫描（OCT）仪器大多是侧视式的，并且依赖于至少一次近端扫描，因此限制了体积成像和正面可视化的准确性。以前的前视 OCT 设备的轴向扫描速度有限。我们报告了一种前视光纤扫描 3D-OCT 探头，具有 900 µm 视场和 5 µm 横向分辨率，以 1 MHz 轴向扫描速率在人体胃肠道中成像。探头直径为 3.3 毫米，刚性长度为 20 毫米，从而能够穿过内窥镜通道。扫描仪具有 1.8 kHz 共振频率，每次体积采集需要 0.17 秒，显示速度为 2 体积/秒。在监测结肠镜检查期间进行结肠 3D-OCT 和血管造影成像。
Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 µm field of view and 5 µm transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes 0.17 s with 2 volumes/s display. 3D-OCT and angiography imaging of the colon was performed during surveillance colonoscopy.