Response of Aedes aegypti (Diptera: Culicidae) larvae to three xenobiotic exposures:: Larval tolerance and detoxifying enzyme activities
Response of Aedes aegypti (Diptera: Culicidae) larvae to three xenobiotic exposures:: Larval tolerance and detoxifying enzyme activities
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DOI：
10.1897/05-267r2.1
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发表时间：
2006-02-01
影响因子：
4.1
通讯作者：
Ravanel, P
中科院分区：
文献类型：
--
作者：
Boyer, S;David, JP;Ravanel, P
蚊子幼虫耐受有毒化合物（temephos，苏云金芽孢杆菌变种）的能力。israelensis，有毒蔬菜落叶）上的实验室埃及伊蚊L。进行生物测定和解毒酶活性测量以比较耐受性/抗性能力。解毒设备的功能可塑性的可能性进行了研究，通过实验测定的诱导作用的每一个异生素在给定的一代。以同样的方式，有毒落叶的选择效果也进行了研究沿着连续几代。结果显示，差异细胞色素P450单加氧酶，酯酶和谷胱甘肽S-转移酶活性水平与生物测定结果相关。无论是诱导和选择增加幼虫的耐受性异生物质的使用，并增加幼虫解毒酶的活性水平。
The ability of mosquito larvae to tolerate toxic compounds (temephos, Bacillus thuringiensis var. israelensis, toxic vegetable leaf litter) was examined on a laboratory larval strain of Aedes aegypti L. Bioassays and detoxifying enzyme activity measurements were performed to compare tolerance/resistance capacities. The possibility of a functional plasticity of detoxifying equipment was investigated through experimental determination of the inductive effect of each xenobiotic within a given generation. In the same way, the selective effect of a toxic leaf litter was also investigated along successive generations. Results revealed that differential cytochrome P450 monooxygenase, esterase, and glutathione S-transferase activity levels correlated with the bioassay results. Both induction and selection increased larval tolerance to the xenobiotics used and increased the levels of larval detoxifying enzyme activities.