Micropatterned carbohydrate displays by self-assembly of glycoconjugate polymers on hydrophobic templates on silicon.
Micropatterned carbohydrate displays by self-assembly of glycoconjugate polymers on hydrophobic templates on silicon.
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DOI：
10.1021/bm049904t
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发表时间：
2004-07
影响因子：
6.2
通讯作者：
Y. Miura;H. Sato;Takayasu Ikeda;H. Sugimura;O. Takai;Kazukiyo Kobayashi
中科院分区：
文献类型：
--
作者：
Y. Miura;H. Sato;Takayasu Ikeda;H. Sugimura;O. Takai;Kazukiyo Kobayashi
我们报告了一种新的策略，微图案化的碳水化合物显示在硅基板上。这种方法利用了疏水-亲水的微制造通过光刻的ODS-SAM在Si衬底上和随后的选择性自组装的糖缀合物聚合物到疏水区域。通过对碳水化合物底物的分子识别的蛋白质微图案化也是成功的。
We report a novel strategy for micropatterned carbohydrate displays on Si substrates. This method exploited the hydrophobic-hydrophilic microfabrication by photolithography of ODS-SAM on Si substrates and the subsequent selective self-assembly of glycoconjugate polymers onto the hydrophobic regions. Protein micropatterning by molecular recognition on the carbohydrate substrates was also successful.