Veto and vacillation: a neural precursor of the decision to withhold action.
Veto and vacillation: a neural precursor of the decision to withhold action.
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否决和犹豫：决定不采取行动的神经前兆。
DOI：
10.1162/jocn_a_00479
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发表时间：
2014
影响因子：
3.2
通讯作者：
Misirlisoy E
中科院分区：
文献类型：
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作者：
Misirlisoy E
抑制计划行动的能力赋予人类行为其特有的灵活性。这一机制是如何运作的，以及什么因素会影响采取行动或不采取行动的决定，目前还相对未被探索。我们使用脑电图准备电位（RPs）来检查正在进行的序列中每个动作之前的准备活动，其中一个动作偶尔被省略。我们比较了由规则（例如，“省略每四个动作”）指示省略的序列和参与者自己自由决定要省略哪个动作的序列之间的rp。对于在自愿遗漏之前立即采取的行动，而不是基于规则的遗漏，RP幅度会减少。我们还使用动作序列的规则时间模式来探索与省略动作相关的大脑过程，通过时间锁定EEG平均值来推断如果不省略动作将发生的时间。当根据规则进行省略时，脑电图中会出现一个负向的趋势，让人想起RP的上升幅度。没有发现自愿遗漏的构成部分。这个结果与一个模型是一致的，在这个模型中，大脑运动区域的自发波动活动可能会影响“自由”决定是否采取行动。
The capacity to inhibit a planned action gives human behavior its characteristic flexibility. How this mechanism operates and what factors influence a decision to act or not act remain relatively unexplored. We used EEG readiness potentials (RPs) to examine preparatory activity before each action of an ongoing sequence, in which one action was occasionally omitted. We compared RPs between sequences in which omissions were instructed by a rule (e.g., “omit every fourth action”) and sequences in which the participant themselves freely decided which action to omit. RP amplitude was reduced for actions that immediately preceded a voluntary omission but not a rule-based omission. We also used the regular temporal pattern of the action sequences to explore brain processes linked to omitting an action by time-locking EEG averages to the inferred time when an action would have occurred had it not been omitted. When omissions were instructed by a rule, there was a negative-going trend in the EEG, recalling the rising ramp of an RP. No such component was found for voluntary omissions. The results are consistent with a model in which spontaneously fluctuating activity in motor areas of the brain could bias “free” decisions to act or not.