Control of Gibbs Free Energy Relationship between Hen-Egg White Lysozyme Polymorphs under Application of an External AC Electric Field
Control of Gibbs Free Energy Relationship between Hen-Egg White Lysozyme Polymorphs under Application of an External AC Electric Field
复制标题
外加交流电场下鸡蛋清溶菌酶多晶型物吉布斯自由能关系的控制
DOI：
10.1107/s002188981200249x
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
J.Nozawa
中科院分区：
文献类型：
--
作者：
Y.Tomita;H.Koizumi;S.Uda;K.Fujiwara;J.Nozawa
在外加交变电场作用下，控制了蛋清溶菌酶体（四方结构）和球型晶体之间的物相分布。由于静电能对两种固相各自化学势的贡献大小不同，相的分布也不同。因此，可以通过改变外加电场的频率来控制两固相之间的吉布斯自由能关系。这种控制多态之间吉布斯自由能关系的方法适用于多种蛋白质。
The distribution of phases between bulk (tetragonal structure) and spherulitic crystals for hen egg white lysozyme was controlled under application of an external alternating current electric field. The distribution of phases differed depending on differences in the magnitude of the electrostatic energy contribution to the respective chemical potentials of the two solid phases. Therefore, the Gibbs free energy relationship between the two solid phases could be controlled by changing the frequency of the applied external electric field. Such a method of controlling the Gibbs free energy relationship among polymorphs would be adaptable to many kinds of protein.