Combined toxicity of microcystin-LR and copper on lettuce (Lactuca sativa L.)
Combined toxicity of microcystin-LR and copper on lettuce (Lactuca sativa L.)
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DOI：
10.1016/j.chemosphere.2018.05.051
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发表时间：
2018-09-01
期刊：
影响因子：
8.8
通讯作者：
Xie, Liqiang
中科院分区：
文献类型：
--
作者：
Cao, Qing;Steinman, Alan D.;Xie, Liqiang
微囊藻毒素和铜通常共存于自然环境中，但它们的联合毒性仍不清楚，特别是在陆生植物中。研究了微囊藻毒素-LR（0、5、50、500、1000 μ g L-1）和铜（0、50、500、1000、2000 μ g L-1）单独和混合处理对生菜萌发、生长和氧化反应的影响。同时对微囊藻毒素-LR和铜的生物累积性进行了评价。结果表明，铜对莴苣萌发的抑制作用与铜与铜的混合物无显著差异，铜与铜的混合物对莴苣萌发的抑制作用表现为简单的相加效应。单独微囊藻毒素-LR没有显着减少，而它是显着减少铜单独和混合物时，铜浓度高于500 μ g L-1。高浓度的微囊藻毒素-LR（1000 μ g L-1）和铜（>= 50 μ g L-1）以及它们的混合物（>= 50 + 500 μ g L-1）诱导莴苣的氧化胁迫。当暴露于低浓度的混合物（= 1000 + 2000 μ g L-1）时，观察到对生菜的生长和抗氧化系统的协同效应。微囊藻毒素-LR与铜的交互作用可增加其在生菜中的积累。我们的研究结果表明，微囊藻毒素-LR和铜的毒性作用加剧时，它们在自然环境中共存，在低浓度下，这不仅会对植物生长产生负面影响，但也构成了潜在的风险，通过食物链对人类健康。(C)2018由Elsevier Ltd.出版
Microcystins and copper commonly co-exist in the natural environment, but their combined toxicity remains unclear, especially in terrestrial plants. The present study investigated the toxicity effects of microcystin-LR (0, 5, 50, 500, 1000 mu g L-1) and copper (0, 50, 500, 1000, 2000 mu g L-1), both individually and in mixture, on the germination, growth and oxidative response of lettuce. The bioaccumulation of microcystin-LR and copper was also evaluated. Results showed that the decrease in lettuce germination induced by copper alone was not significantly different from that induced by the mixture, and the combined toxicity assessment showed a simple additive effect. Lettuce growth was not significantly reduced by microcystin-LR alone, whereas it was significantly reduced by copper alone and the mixture when copper concentration was higher than 500 mu g L-1. High concentrations of microcystin-LR (1000 mu g L-1) and copper (>= 50 mu g L-1),as well as their mixture (>= 50 + 500 mu g L-1), induced oxidative stress in lettuce. A synergistic effect on the growth and antioxidative system of lettuce was observed when exposed to low concentrations of the mixture (= 1000 + 2000 mu g L-1). Moreover, the interaction of microcystin-LR and copper can increase their accumulation in lettuce. Our results suggest that the toxicity effects of microcystin-LR and copper are exacerbated when they co-exist in the natural environment at low concentrations, which not only negatively affects plant growth but also poses a potential risk to human health via the food chain. (C) 2018 Published by Elsevier Ltd.