An autopsy case of Brugada syndrome with significant lesions in the sinus node

An autopsy case of Brugada syndrome with significant lesions in the sinus node
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DOI:
10.1046/j.1540-8167.2004.40378.x
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发表时间:
2005-03-01
影响因子:
2.7
通讯作者:
Hishida, H
Hishida, H
中科院分区:
医学3区
文献类型:
--
作者:
Morimoto, S;Uemura, A;Hishida, H

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一名患有Brugada综合征的30岁男子突然死亡。这颗心脏重380克。左室壁轻度增厚,右室流出道脂肪组织沉积明显。两心室均未扩大。双心室弥漫性收缩带坏死。心室未见心肌细胞肥大、萎缩或明显间质纤维化。窦房结的结细胞数量减少一半,脂肪组织和纤维化突出。但右束支未见明显病变。
A 30-year-old man with Brugada syndrome died suddenly. The heart weighed 380 g. The left ventricular wall showed mild thickening, and marked fatty tissue deposition was noted in the right ventricular outflow tract. Neither ventricle was enlarged. Contraction band necrosis was diffuse in both ventricles. In the ventricles no cardiac muscle cell hypertrophy or atrophy, or significant interstitial fibrosis was observed. In the sinus node the number of nodal cells was reduced by half, with fatty tissue and fibrosis prominent. But no lesions were evident in the right bundle branch.