N95 Respirators for Cardiovascular Protection During Wildfire Smoke Events.
N95 Respirators for Cardiovascular Protection During Wildfire Smoke Events.
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用于野火烟雾事件期间心血管保护的 N95 呼吸器。
DOI：
10.1161/jaha.123.032422
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发表时间：
2024
影响因子：
5.4
通讯作者：
Al-Kindi,Sadeer
中科院分区：
文献类型：
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作者：
Brook,RobertD;Rajagopalan,Sanjay;Al-Kindi,Sadeer
2023年，野火烟雾（WFS）影响了美国中西部/东部。数千万人暴露在非常不健康的空气中。1这是一个严重的公共卫生威胁，因为预计此类事件会增加，因为WFS会导致许多健康问题，包括心血管发病率和死亡率。2 <2. 5 μm的细颗粒物（PM2. 5)被认为是罪魁祸首因此，个人可以采取的保护健康的行动，包括佩戴N95呼吸器，引起了相当大的关注。[3]尽管公众对呼吸器的使用几乎没有进行过科学审查。2、4台N95净化器可降低PM2. 5暴露时，适当的配合和磨损;然而，其在现实世界中的有效性仍然未知。4即使假设最好的情况下，在WFS事件期间大规模N95呼吸器运动以保护公众的可行性和所需成本也需要仔细考虑。支持本研究的数据可根据合理要求从相应作者处获得。无需机构审查委员会批准。我们根据美国成年人群以及中、高危人群的数据，估计了使用N95呼吸机预防1例动脉粥样硬化性心血管疾病（ASCVD）事件（致死性或非致死性心肌梗死或卒中）所需治疗的人数（NNT 1）。我们估计，在WFS暴露期间，ASCVD事件的风险每天增加20
Wildfire smoke (WFS) impacted the Midwest/Eastern United States during 2023. Tens of millions of people were exposed to very unhealthy air. 1 This represents a serious public health threat as such events are expected to increase and because WFS causes many health issues including cardiovascular morbidity and mortality. 2 Fine particulate matter< 2.5 μm (PM2. 5) is considered the principal culprit. Actions that individuals can take to protect their health, including wearing N95 respirators, have thus garnered considerable attention. 3 This is despite the fact that respirator use in the general public has undergone little scientific scrutiny. 2, 4 N95 respirators can reduce PM2. 5 exposure when properly fit and worn; however, their effectiveness in real-world settings remains unknown. 4 Even assuming best-case scenarios, the feasibility and costs required for large-scale N95 respirator campaigns to protect the public during WFS events require careful consideration.Data supporting this study are available from the corresponding author upon reasonable request. Institutional Review Board approval was not required. We estimated the number needed to treat (NNT1) to prevent 1 atherosclerotic cardiovascular disease (ASCVD) event (fatal or nonfatal myocardial infarction or stroke) by using an N95 respirator based on data for the US adult population as well as intermediate-and high-risk populations. We estimated a 20% increase in risk per day for ASCVD events during WFS exposure