Enhancement of ozone-induced lung injury by exercise.
Enhancement of ozone-induced lung injury by exercise.
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运动增强臭氧引起的肺损伤。
DOI：
10.1080/15287398509530792
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
T. Crocker
中科院分区：
文献类型：
--
作者：
William;Mautz;T. McClure;Peter Reischl;R. Phalen;T. Crocker
大鼠暴露于0.20-0.80 ppm O3的条件下，休息和跑步机运动高达30米/分钟，20%的等级，以评估暴露时间，O3浓度和运动对肺组织损伤的重要性。局灶性肺实质病变增加的丰度和严重程度的三个变量的反应，但是，运动是最重要的。病变对运动的反应大于预测的一个简单的比例，估计有效剂量的O3。结果强调了在评估暴露于空气污染物可能对健康产生的不利影响时，包括运动的重要性。
Rats were exposed for up to 3.75 h to 0.20-0.80 ppm O3 under conditions of rest and treadmill exercise up to 30 m/min, 20% grade, to assess the importance of exposure duration, O3 concentration, and exercise on lung tissue injury. Focal lung parenchymal lesions increased in abundance and severity in response to the three variables; however, exercise was the most important. Lesion response to exercise was greater than that predicted by a simple proportion to estimated effective dose of O3. The results emphasize the importance of including exercise in assessment of possible adverse health effects of exposure to airborne pollutants.