Biomagnetic systems for clinical use

Biomagnetic systems for clinical use
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DOI:
10.1080/01418630008221960
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发表时间:
2000-05-01
期刊:
PHILOSOPHICAL MAGAZINE B-PHYSICS OF CONDENSED MATTER STATISTICAL MECHANICS ELECTRONIC OPTICAL AND MAGNETIC PROPERTIES
影响因子:
--
通讯作者:
Erné, SN
Erné, SN
中科院分区:
其他
文献类型:
--
作者:
Della Penna, S;Del Gratta, C;Erné, SN

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我们展示了两个基于超导量子干涉装置 (SQUID) 的多通道系统,用于生物磁测量,安装在基耶蒂大学。这两个系统都是为临床和常规使用而设计的,并且是通过国际合作开发的。仪器实施中的主要问题是场灵敏度和空间分辨率,以及操作过程中的灵活性和稳定性。第一个系统是平面系统,设计用于心磁图测量。该系统由低噪声杜瓦瓶中包含的 74 个 de SQUID 集成磁力计组成:55 个传感器是测量通道,21 个传感器放置在远离主体的位置,用作创建软件梯度计的参考通道。第二个系统是头盔系统,由 165 个 de SQUID 集成磁力计组成,用于执行脑磁图记录; 153个通道分布在覆盖整个头皮的表面上,其中12个通道用作参考。 SQUID 磁力计的场噪声约为 5 fT Hz(-1/2)。每个系统均置于磁屏蔽室内,进行涡流屏蔽和磁屏蔽。磁场以高达 10 kHz 的采样频率进行记录。模数转换后的数据通过数字信号处理器阵列进行在线处理,从而实现带通滤波、抽取和噪声补偿。
We present two multichannel systems based on a superconducting quantum interference device (SQUID) for biomagnetic measurements, installed at the University of Chieti. Both systems have been designed for clinical and routine use and have been developed owing to an international cooperation. The main issues in the instrument implementation were field sensitivity and spatial resolution, as well as flexibility and stability during operation. The first system is a planar system and is devised for magnetocardiographic measurements. This system is composed of 74 de SQUID integrated magnetometers contained in a low-noise dewar: 55 sensors are measurement channels and 21 are placed far from the subject and are used as reference channels to create software gradiometers. The second system is a helmet system and consists of 165 de SQUID integrated magnetometers to perform magnetoencephalographic recordings; 153 channels are distributed over a surface covering the whole scalp and 12 channels are used as references. The field noise of the SQUID magnetometers is about 5 fT Hz(-1/2). Each system is placed in a magnetically shielded room for eddy current shielding and magnetic shielding. The magnetic field is recorded with sampling frequencies up to 10 kHz. The analogue-to-digital converted data are processed on line by means of an array of digital signal processors, allowing bandpass filtering, decimation and noise compensation.