Reliability of the time trade-off technique of utility assessment in patients with retinal disease.
Reliability of the time trade-off technique of utility assessment in patients with retinal disease.
复制标题
视网膜疾病患者效用评估的时间权衡技术的可靠性。
DOI：
10.1097/00132578-200207000-00025
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
S. Sharma
中科院分区：
文献类型：
--
作者：
H. Hollands;M. Lam;J. Pater;D. Albiani;G. Brown;M. Brown;A. Cruess;S. Sharma
背景
在眼科以外的医学领域的研究已经给出了关于效用评估的时间权衡技术的可靠性的相互矛盾的结果。我们进行了一项研究，以确定时间权衡技术的重新测试的可靠性，以评估与视网膜眼病患者的效用，并调查可能的因素与效用随时间的差异。
方法
转诊至加拿大东部三级护理医院视网膜服务的患者，如果他们至少有一只眼睛的最佳矫正视力为20/30或更差，并且被认为有能力回答所需问题，则有资格进行初步访谈。在1999年12月至2000年3月期间，在药物性瞳孔散大发生所需的正常30分钟期间，对患者进行前瞻性访谈。通过病历回顾和标准化访谈收集人口统计学、临床（包括Snellen视力）和时间权衡效用信息。成功完成访谈的患者在28天后被召回进行随访。
结果
在138例合格患者中，112例（81.2%）完成了初始访谈。在112人中，96人（85.7%）完成了第二次面试。一半的受访者是女性，除一人外，所有受访者都是白色。平均年龄为65.3岁。视力丧失的主要原因包括糖尿病视网膜病变（59例患者[61.4%]）和年龄相关性黄斑变性（14例患者[14.6%]）。初始和随访视觉效用之间的组内相关系数为0.7634（95%置信区间0.6655-0.8355）。
解释
我们的研究结果显示了良好的可靠性的时间权衡技术的效用评估患者的视网膜眼病。
BACKGROUND
Studies in medical fields other than ophthalmology have given conflicting results regarding the reliability of the time trade-off technique of utility assessment. We performed a study to determine the test-retest reliability of the time trade-off technique for assessing utilities in patients with ocular diseases of the retina and to investigate possible factors associated with differences in utility over time.
METHODS
Patients referred to the retina service of a tertiary care hospital in eastern Canada were eligible for the initial interview if they had best corrected vision of 20/30 or worse in at least one eye and were deemed competent to answer the required questions. Patients were interviewed prospectively between December 1999 and March 2000 during a normal 30-minute period needed for pharmacologic mydriasis to occur. Demographic, clinical (including Snellen visual acuity) and time trade-off utility information was collected through chart review and standardized interview. Patients who completed the interview successfully were called back 28 days later for follow-up.
RESULTS
Of the 138 eligible patients 112 (81.2%) completed the initial interview. Of the 112, 96 (85.7%) completed the second interview. Half of the respondents were women, and all but one respondent were white. The mean age was 65.3 years. The primary reasons for visual loss included diabetic retinopathy (59 patients [61.4%]) and age-related macular degeneration (14 patients [14.6%]). The intraclass correlation coefficient between the initial and follow-up visual utilities was 0.7634 (95% confidence interval 0.6655-0.8355).
INTERPRETATION
Our results show excellent reliability of the time trade-off technique of utility assessment in patients with ocular diseases of the retina.
DOI：
10.1016/s0022-5347(01)64043-6
发表时间：
1998
期刊：
The Journal of urology
影响因子：
--
作者：
Albertsen,PC;NeaseJr,RF;Potosky,AL
通讯作者：
Potosky,AL