Prevalence and correlates of depressed mood among youth with diabetes: The SEARCH for Diabetes in Youth study
Prevalence and correlates of depressed mood among youth with diabetes: The SEARCH for Diabetes in Youth study
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DOI：
10.1542/peds.2005-1398
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发表时间：
2006-04-01
期刊：
影响因子：
8
通讯作者：
McKeown, RE
中科院分区：
文献类型：
--
作者：
Lawrence, JM;Standiford, DA;McKeown, RE
OBJECTIVE.本研究的目的是确定青年糖尿病患者的抑郁情绪是否与糖尿病的类型和病程、平均糖化血红蛋白（HbA 1c）水平、糖尿病酮症酸中毒（DKA）和低血糖发作的频率、住院和急诊（艾德）就诊有关。共有2672名平均病程为5年的糖尿病青年（年龄10 - 21岁）完成了一项研究访视，其中测量了他们的HbA 1c，并收集了关于他们的人口统计学特征、糖尿病类型和病程以及过去6个月内DKA、低血糖、住院和艾德访视的信息。采用流行病学研究中心抑郁量表（CES-D）测量他们的抑郁情绪水平。在这些年轻人中，14%有轻度（CES-D 16 - 23）和8.6%有中度或重度（CES-D >= 24）抑郁情绪。女性的平均CES-D评分高于男性。在调整了人口统计学因素和糖尿病持续时间后，我们发现男性2型糖尿病患者的抑郁情绪患病率高于1型糖尿病患者，女性合并症患者的抑郁情绪患病率高于无合并症患者。较高的平均HbA 1c和艾德就诊频率与抑郁情绪相关。糖尿病青年抑郁情绪的患病率与发表的非糖尿病青年抑郁情绪的估计值相似。医生和其他卫生保健专业人员应考虑在临床环境中筛查糖尿病青年患者的抑郁情绪，特别是血糖控制不良的青年，经常艾德就诊的青年，2型糖尿病男性和合并症女性。
OBJECTIVE. The objective of this study was to determine if depressed mood among youth with diabetes was associated with type and duration of diabetes, mean glycosylated hemoglobin (HbA1c) level, and the frequency of diabetic ketoacidosis (DKA) and hypoglycemic episodes, hospitalizations, and emergency department (ED) visits.METHODS. A total of 2672 youth ( aged 10 - 21 years) who had diabetes for a mean duration of 5 years completed a SEARCH study visit, in which their HbA1c was measured and information about their demographic characteristics, diabetes type and duration, and episodes of DKA, hypoglycemia, hospitalizations, and ED visits over the previous 6 months was collected. Their level of depressed mood was measured using the Center for Epidemiologic Studies Depression Scale (CES-D).RESULTS. Among these youth, 14% had mildly (CES-D 16 - 23) and 8.6% had moderately or severely (CES-D >= 24) depressed mood. Females had a higher mean CES-D score than males. After adjusting for demographic factors, and duration of diabetes, we found the prevalence of depressed mood to be higher among males with type 2 diabetes than those with type 1 diabetes and to be higher among females with comorbidities than those without comorbidities. Higher mean HbA1c and frequency of ED visits were associated with depressed mood. The prevalence of depressed mood among youth with diabetes was similar to that of published estimates of depressed mood among youth without diabetes.CONCLUSIONS. Physicians and other health care professionals should consider screening youth with diabetes for depressed mood in clinical settings, particularly youth with poor glycemic control, those with a history of frequent ED visits, males with type 2 diabetes, and females with comorbidities.