Subjective quality of life in first episode schizophrenia spectrum disorders with comorbid depression
Subjective quality of life in first episode schizophrenia spectrum disorders with comorbid depression
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DOI：
10.1016/j.psychres.2004.07.007
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发表时间：
2004-12-15
影响因子：
11.3
通讯作者：
Chong, SA
中科院分区：
文献类型：
--
作者：
Sim, K;Mahendran, R;Chong, SA
先前的研究报道了抑郁症状或综合征在首发精神病患者中的高患病率，但缺乏这些患者生活质量（QOL）的数据。本横断面研究旨在比较这些有和没有共病抑郁综合征的个体在基线时的主观生活质量。采用结构化临床访谈诊断DSM iv - I轴障碍、精神障碍无意识评定量表（SUMD）、阳性和阴性综合征量表（PANSS）、汉密尔顿抑郁评定量表（HAIM-D）和世界卫生组织生活质量量表（WHOQOL-BREF），对66例连续首发精神分裂症谱系障碍(精神分裂症、在我们的早期精神病干预项目中。我们发现，共病抑郁综合征的受试者对自己的精神疾病、社会后果和治疗效果有更高的认识，但总体生活质量较差。尤其是在身体、心理健康方面。社会关系和环境领域。伴随抑郁综合征受试者的生活质量较差可能是由于这些患者的洞察力更强，他们将自己的问题归因于健康状况不佳、社会支持不满意和消极环境。其他解释也是可能的。为心理支持和干预提供可能的焦点。2004爱思唯尔爱尔兰有限公司版权所有。
Previous studies have reported high prevalence rates of depressive symptoms or syndromes in subjects with first episode psychosis, but data are lacking on the quality of life (QOL) in these subjects. This cross-sectional study seeks to compare the subjective QOL of these individuals with and without a comorbid depressive syndrome at baseline. Using the Structured Clinical Interview to Diagnose DSM IV-Axis I Disorders, the Scale to Assess Unawareness of Mental Disorders (SUMD), Positive and Negative Syndrome Scale (PANSS), Hamilton Rating Scale for Depression (HAIM-D), and the World Health Organization Quality of Life-Bref Scale (WHOQOL-BREF), we evaluated 66 consecutive subjects with first episode schizophrenia spectrum disorders (schizophrenia, schizoaffective and schizophreniform disorders) in our Early Psychosis Intervention Program. We found that subjects with a comorbid depressive syndrome had greater awareness of their mental illness, its social consequences and treatment efficacy, but poorer overall QOL. especially in the physical, psychological health. social relationships and environmental domains. The poorer QOL in subjects with a comorbid depressive syndrome may be explained by the greater degree of insight in these patients and their attributing their troubles to poor health, unsatisfactory social support and negative environment. Alternative explanations are also possible. providing possible foci for psychological support and intervention. (C) 2004 Elsevier Ireland Ltd. All rights reserved.