Origin of Mexican Nahuas (Aztecs) according to HLA genes and their relationships with worldwide populations
Origin of Mexican Nahuas (Aztecs) according to HLA genes and their relationships with worldwide populations
复制标题
DOI：
10.1016/j.molimm.2006.04.014
复制
发表时间：
2007-02-01
影响因子：
3.6
通讯作者：
Arnaiz-Villena, Antonio
中科院分区：
文献类型：
--
作者：
Vargas-Alarcon, Gilberto;Moscoso, Juan;Arnaiz-Villena, Antonio
对来自墨西哥莫雷洛斯州的一群纳华阿兹特克人的人类白细胞抗原进行了研究。利用13,818条染色体，通过计算Nei‘s Chord遗传距离(DA)、邻接树形图和对应多维值，研究了该群体与其他美洲印第安人和世界各地人群的关系。在本组中发现了三种新的人类白细胞抗原扩展单倍型：A*30-B*49-DRB1*1001-DQBI*0501(该群体中最常见的一种)，A*02-B*52-DQBI*1402-DQBI*0301和A*68-B*61-DRBI*1602-DQBI*0303。两种遗传距离和对应分析都清楚地表明，我们的纳尔马隔离群体在遗传上与墨西哥最古老的群体(玛雅人，玛雅人)接近Zapotecans，Mixtecans)。这表明，纳瓦语(纳瓦特尔)可能被强加给墨西哥各地分散的群体；否则，阿兹特克人在公元12世纪假定移民之前很久就已经生活在墨西哥了。(C)2006爱思唯尔有限公司。保留所有权利。
A Nahua Aztec isolated group from Morelos State (Mexico) was studied for their HLA profile. The relationship with other Amerindians and worldwide populations was studied by using 13,818 chromosomes and calculating Nei's chord genetic distances (DA), neighbor-joining dendrograms and correspondence multidimensional values.Three new HLA extended haplotypes were found in our group: A*30-B*49-DRB1*1001-DQBI*0501 (the most frequent one in this population), A*02-B*52-DRBI*1402-DQBI*0301 and A*68-B*61-DRBI*1602-DQBI*0303.Both genetic distances and correspondence analyses clearly show that our Nalma isolated group is genetically close to some of the most ancient groups living in Mexico (Mayans, Zapotecans, Mixtecans). This suggests that Nahua language (Nahuatl) may have been imposed to scattered groups throughout Mexico; otherwise Aztecs may have been living in Mexico long before their postulated immigration in the XII century AD. (c) 2006 Elsevier Ltd. All rights reserved.