Physiology of Extracorporeal Life Support (ECLS)
Physiology of Extracorporeal Life Support (ECLS)
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DOI：
10.1007/978-1-4939-3005-0_1
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发表时间：
2016-01-01
期刊：
影响因子：
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通讯作者：
MacLaren, Graeme
中科院分区：
文献类型：
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作者：
Brain, Matthew J.;Butt, Warwick W.;MacLaren, Graeme
体外生命支持（ECLS）描述了几种扩大范围的先进技术，用于支持危重患者的严重心肺功能障碍。当机械通气不足以提供足够的氧合或二氧化碳清除时，ECLS提供了替代方案。静脉-静脉体外膜肺氧合（VV-ECMO）支持静脉血中的气体交换返回右心。ECLS还可以配置为提供衰竭循环的机械支持;静脉-动脉体外膜氧合（VA-ECMO）利用体外血泵增加体循环血流量。由于患者可能严重依赖这些支持，因此对系统及其与身体的相互作用的透彻理解对于应用ECLS以及预防或改善可能出现的问题至关重要。
Extracorporeal life support (ECLS) describes several advancing technologies of broadening scope that support severe cardiorespiratory dysfunction in critically ill patients. ECLS provides alternatives when mechanical ventilation does not suffice to deliver adequate oxygenation or carbon dioxide clearance. Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports gas exchange in venous blood returning to the right heart. ECLS can also be configured to provide mechanical support of the failing circulation; veno-arterial extracorporeal membrane oxygenation (VA-ECMO) augments systemic blood flow utilising the extracorporeal blood pump. As patients can be critically dependent on these supports, a thorough understanding of the systems and their interaction with the body is essential in applying ECLS and in preventing or ameliorating problems that can arise.