Head tremor in cervical dystonia: Quantifying severity with computer vision.
Head tremor in cervical dystonia: Quantifying severity with computer vision.
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DOI：
10.1016/j.jns.2022.120154
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发表时间：
2022-03-15
影响因子：
4.4
通讯作者：
Peterson, David A.
中科院分区：
文献类型：
--
作者：
Vu, Jeanne P.;Cisneros, Elizabeth;Lee, Ha Yeon;Le, Linh;Chen, Qiyu;Guo, Xiaoyan A.;Rouzbehani, Ryin;Jankovic, Joseph;Factor, Stewart;Goetz, Christopher G.;Barbano, Richard L.;Perlmutter, Joel S.;Jinnah, Hyder A.;Richardson, Sarah Pirio;Stebbins, Glenn T.;Elble, Rodger;Comella, Cynthia L.;Peterson, David A.
头颤（HT）是颈肌张力障碍（CD）的共同特征，通常通过主观观察来量化。技术的发展为测量高温严重程度提供了客观且易于自动化的替代方法。我们的目标是开发一种基于计算机视觉的软件系统，用于在临床检查期间从视频记录中量化HT的振荡和定向方面，并测试其与临床评定量表的收敛有效性。对于由肌张力障碍联盟登记的93名患有孤立性CD和HT的参与者，我们分析了一个检查片段的视频记录，其中参与者被指示让他们的头部漂移到最舒适的肌张力障碍位置。我们评估了峰值功率、频率和定向优势，并使用Spearman相关性来衡量cor与临床评分之间的一致性。平均功率为0.90 (SD 1.80) deg2/Hz，峰值频率为1.95 (SD 0.94) Hz。主导的HT轴是俯仰（前/后倾）占50%，侧倾（侧倾）占6%，偏航（斜颈）占44%。单侧t检验显示次要HT轴（t = 18.17, p < 0.0001）和第三次HT轴（t = 12.89, p < 0.0001）有很大贡献。CMOR的HT严重程度测量与多伦多西部痉挛性斜颈评定量表-2中的HT项目正相关（Spearman’s rho = 0.54, p < 0.001）。我们展示了一种新的测量HT严重程度的客观方法，该方法只需要传统的视频记录，量化了CD中HT的复杂性，并显示了与临床严重程度评级的收敛有效性。
Head tremor (HT) is a common feature of cervical dystonia (CD), usually quantified by subjective observation. Technological developments offer alternatives for measuring HT severity that are objective and amenable to automation. Our objectives were to develop CMOR (Computational Motor Objective Rater; a computer vision-based software system) to quantify oscillatory and directional aspects of HT from video recordings during a clinical examination and to test its convergent validity with clinical rating scales. For 93 participants with isolated CD and HT enrolled by the Dystonia Coalition, we analyzed video recordings from an examination segment in which participants were instructed to let their head drift to its most comfortable dystonic position. We evaluated peak power, frequency, and directional dominance, and used Spearman’s correlation to measure the agreement between CMOR and clinical ratings. Power averaged 0.90 (SD 1.80) deg2/Hz, and peak frequency 1.95 (SD 0.94) Hz. The dominant HT axis was pitch (antero/retrocollis) for 50%, roll (laterocollis) for 6%, and yaw (torticollis) for 44% of participants. One-sided t-tests showed substantial contributions from the secondary (t = 18.17, p < 0.0001) and tertiary (t = 12.89, p < 0.0001) HT axes. CMOR’s HT severity measure positively correlated with the HT item on the Toronto Western Spasmodic Torticollis Rating Scale-2 (Spearman’s rho = 0.54, p < 0.001). We demonstrate a new objective method to measure HT severity that requires only conventional video recordings, quantifies the complexities of HT in CD, and exhibits convergent validity with clinical severity ratings.
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影响因子：
3.3
作者：
Boccagni, Cristina;Carpaneto, Jacopo;Galardi, Giuseppe
通讯作者：
Galardi, Giuseppe
影响因子：
8.6
作者：
Albanese, Alberto;Bhatia, Kailash;Bressman, Susan B.;DeLong, Mahlon R.;Fahn, Stanley;Fung, Victor S. C.;Hallett, Mark;Jankovic, Joseph;Jinnah, Hyder A.;Klein, Christine;Lang, Anthony E.;Mink, Jonathan W.;Teller, Jan K.
通讯作者：
Teller, Jan K.
DOI：
10.1002/mds.26534
发表时间：
2016-04
期刊：
Movement disorders : official journal of the Movement Disorder Society
影响因子：
--
作者：
Comella CL;Perlmutter JS;Jinnah HA;Waliczek TA;Rosen AR;Galpern WR;Adler CA;Barbano RL;Factor SA;Goetz CG;Jankovic J;Reich SG;Rodriguez RL;Severt WL;Zurowski M;Fox SH;Stebbins GT
通讯作者：
Stebbins GT
DOI：
10.1109/jtehm.2020.3032924
发表时间：
2021
影响因子：
3.4
作者：
Mcgurrin P;Mcnames J;Wu T;Hallett M;Haubenberger D
通讯作者：
Haubenberger D
影响因子：
11
作者：
Defazio, Giovanni;Gigante, Angelo Fabio;Berardelli, Alfredo
通讯作者：
Berardelli, Alfredo