Flow visualization study to improve hemocompatibility of a centrifugal blood pump.
Flow visualization study to improve hemocompatibility of a centrifugal blood pump.
复制标题
提高离心血泵血液相容性的流动可视化研究。
DOI：
10.1046/j.1525-1594.1999.06400.x
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发表时间：
1999
影响因子：
2.4
通讯作者：
Y. Konishi
中科院分区：
文献类型：
--
作者：
M. Nishida;B. Asztalos;T. Yamane;T. Masuzawa;T. Tsukiya;S. Endo;Y. Taenaka;Y. Miyazoe;K. Ito;Y. Konishi
对离心式血泵内的流动进行了定量流动可视化分析、计算流体动力学分析和溶血试验之间的相关性研究，以防止溶血。特别注意了叶轮/机壳间隙宽度对蜗壳内和出口内流动的影响。使用Ar离子激光光片、高速摄像机和粒子跟踪测速仪，获得了不同几何尺寸的250%放大模型的流动矢量图。结果表明，在径向小径向缝隙模型中，出口内壁附近出现高剪切，出口外壁附近出现滞流，而标准模型则保持流动平稳，剪切较低。小径向间隙模型显示出比标准模型更低的头部和更大的溶血。这种下降可以通过重新调整出口位置来部分恢复，但溶血水平几乎没有下降。从这些结果可以看出，小的径向间隙本身是重要的。壁面附近详细的流动显示和简单的层流剪切分析也证实，较小的径向间隙导致了比标准模型(约80微米)更宽的高剪切层(110-120微米)。在小径向间隙模型中，出口的高剪切层(约50微米)比蜗壳内的高剪切层窄得多。流动可视化结合计算流体动力学分析将有助于消除溶血的原因。
A correlation study was conducted among quantitative flow visualization analysis, computational fluid dynamic analysis, and hemolysis tests regarding the flow in a centrifugal blood pump to prevent hemolysis. Particular attention was paid to the effect of the impeller/casing gap widths on the flow in the volute and in the outlet. Flow vector maps were obtained for 250% scaled-up models with various geometries, using an argon ion laser light sheet, a high speed video camera, and particle tracking velocimetry. In terms of the results, in the small radial gap model, high shear occurred near the inside wall of the outlet and stagnation near the outside wall of the outlet whereas the standard model maintained smooth flow and low shear. The small radial gap model showed a lower head and greater hemolysis than the standard model. This head decrease could be partly restored by relocating the outlet position; however, the hemolysis level hardly decreased. From these results, it was found that the small radial gap itself is important. It was also confirmed by detailed flow visualization and simple laminar shear analysis near the wall that the small radial gap caused a wider high shear layer (110-120 microm) than the standard model (approximately 80 microm). In the small radial gap model, the high shear layer in the outlet (approximately 50 microm) is much narrower than that in the volute. Flow visualization together with the aid of computational fluid dynamic analysis would be useful to eliminate the causes of hemolysis.