Sample illumination device facilitates in situ light-coupled NMR spectroscopy without fibre optics.
Sample illumination device facilitates in situ light-coupled NMR spectroscopy without fibre optics.
复制标题
样品照明装置便于在没有光纤的情况下进行原位光耦合NMR光谱分析。
DOI：
10.1038/s42004-022-00704-5
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发表时间：
2022-08-04
影响因子：
5.9
通讯作者：
Golovanov, Alexander P.
中科院分区：
文献类型：
--
作者：
Bramham, Jack E.;Golovanov, Alexander P.
液态核磁共振样品的原位照明使得利用强大的分析技术研究一系列与光相关的化学和生物现象成为可能。然而，核磁共振样品的位置在光谱仪磁铁的内孔深处，这使得这种照明具有挑战性。在这里，我们演示了一种样品照明装置(NMRtorch)的工作原理，在该装置中，包含LED阵列的灯头直接位于插入到核磁共振光谱仪中的NMR炬管的顶部。试管的管壁本身起到了导光的作用，从外部照亮了样品。我们探索了这种新的设置如何在一些光-核磁共振应用中执行，包括光异构化和光化学诱导的动态核极化(PHOTO-CIDNP)，并通过连续的在线核磁共振评估展示了紫外线(UV)降解研究的潜力。这种设置使任何典型的液态光谱仪的用户能够使用广泛的波长轻松地进行原位光-核磁共振实验。液态核磁共振样品的原位照明允许表征依赖于光的化学和生物现象，但在实践中，核磁共振样品在光谱仪磁体孔中的位置使得这种照明具有挑战性。本文介绍了一种样品照明装置的工作原理，将LED阵列直接放置在特殊样品管的顶部，将样品管插入到核磁共振光谱仪中。
In situ illumination of liquid-state nuclear magnetic resonance (NMR) samples makes it possible for a wide range of light-dependent chemical and biological phenomena to be studied by the powerful analytical technique. However, the position of an NMR sample deep within the bore of the spectrometer magnet renders such illumination challenging. Here, we demonstrate the working principles of a sample illumination device (NMRtorch) where a lighthead containing an LED array is positioned directly at the top of an NMRtorch tube which is inserted into the NMR spectrometer. The wall of the tube itself acts as a light guide, illuminating the sample from the outside. We explore how this new setup performs in a number of photo-NMR applications, including photoisomerisation and photo-chemically induced dynamic nuclear polarisation (photo-CIDNP), and demonstrate the potential for ultraviolet (UV) degradation studies with continuous online NMR assessment. This setup enables users of any typical liquid-state spectrometer to easily perform in situ photo-NMR experiments, using a wide range of wavelengths. In situ illumination of liquid-state NMR samples allows to characterise light-dependent chemical and biological phenomena, but, in practice, the position of an NMR sample deep within the bore of a spectrometer magnet renders such illumination challenging. Here, the authors demonstrate the working principles of a sample illumination device, with an LED array positioned directly at the top of special sample tube, which is inserted into the NMR spectrometer.
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影响因子：
16.6
作者：
Oezgen, F. Feyza;Runda, Michael E.;Schmidt, Sandy
通讯作者：
Schmidt, Sandy
影响因子：
16.6
作者：
Hoorens, Mark W. H.;Medved, Miroslav;Szymanski, Wiktor
通讯作者：
Szymanski, Wiktor
影响因子：
15
作者：
Kuprov, Ilya;Craggs, Timothy D.;Hore, P. J.
通讯作者：
Hore, P. J.
DOI：
10.1002/cphc.201800570
发表时间：
2018-10-05
期刊：
Chemphyschem : a European journal of chemical physics and physical chemistry
影响因子：
--
作者：
Bernarding J;Euchner F;Bruns C;Ringleb R;Müller D;Trantzschel T;Bargon J;Bommerich U;Plaumann M
通讯作者：
Plaumann M
影响因子：
15
作者：
Bartling, Hanna;Eisenhofer, Anna;Gschwind, Ruth M.
通讯作者：
Gschwind, Ruth M.