The "Goldilocks Day" for Children's Skeletal Health: Compositional Data Analysis of 24-Hour Activity Behaviors
The "Goldilocks Day" for Children's Skeletal Health: Compositional Data Analysis of 24-Hour Activity Behaviors
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DOI：
10.1002/jbmr.4143
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发表时间：
2020-09-23
影响因子：
6.2
通讯作者：
Olds, Timothy
中科院分区：
文献类型：
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作者：
Dumuid, Dorothea;Simm, Peter;Olds, Timothy
优化儿童骨骼健康的活动行为是一个关键的公共卫生优先事项，但目前还不清楚多少小时的中度到剧烈的体力活动（MVPA），轻度体力活动（LPA），久坐不动的行为，或睡眠构成了最好的一天-“金发女孩日”-为儿童的骨骼结构和功能。为了描述儿童骨骼健康的最佳一天，我们使用了来自儿童健康检查点的数据。纳入的参与者（n= 804，年龄10.7 - 12.9岁，50%男性）接受胫骨外周定量CT，以评估横截面积、骨小梁和皮质密度、骨膜和骨内膜周长、极惯性矩和极应力应变指数。通过8天24小时加速度计评估平均每日时间使用组成（MVPA、LPA、久坐时间和睡眠）。Skeleton结果与时间使用组成进行回归，表示为等距对数比（如有指示，则使用二次项），并根据性别，年龄，青春期状态和社会经济地位进行调整。该模型被用来估计最佳的时间使用组合物（与最好的5%的每个骨骼的结果），这是绘制在三维四元图。重叠区域的中心被认为是骨骼健康的金发女孩日。儿童的时间利用结构与所有骨骼测量（ALLP）相关
Optimization of children's activity behaviors for skeletal health is a key public health priority, yet it is unknown how many hours of moderate to vigorous physical activity (MVPA), light physical activity (LPA), sedentary behavior, or sleep constitute the best day-the "Goldilocks Day"-for children's bone structure and function. To describe the best day for children's skeletal health, we used data from the cross-sectional Child Health CheckPoint. Included participants (n= 804, aged 10.7 to 12.9 years, 50% male) underwent tibial peripheral quantitative CT to assesses cross-sectional area, trabecular and cortical density, periosteal and endosteal circumference, polar moment of inertia, and polar stress-strain index. Average daily time-use composition (MVPA, LPA, sedentary time, and sleep) was assessed through 8-day, 24-hour accelerometry. Skeletal outcomes were regressed against time-use compositions expressed as isometric log-ratios (with quadratic terms where indicated), adjusted for sex, age, pubertal status, and socioeconomic position. The models were used to estimate optimal time-use compositions (associated with best 5% of each skeletal outcome), which were plotted in three-dimensional quaternary figures. The center of the overlapping area was considered the Goldilocks Day for skeletal health. Children's time-use composition was associated with all skeletal measures (allp