Serum concentrations of β-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population
Serum concentrations of β-carotene, vitamins C and E, zinc and selenium are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population
复制标题
DOI：
10.1038/sj.ejcn.1602230
复制
发表时间：
2005-10-01
影响因子：
4.7
通讯作者：
Hercberg, S
中科院分区：
文献类型：
--
作者：
Galan, P;Viteri, FE;Hercberg, S
目的：评估能量、营养素和食物摄入量、饮酒量、吸烟状况和体重指数（BMI）以及血清β-胡萝卜素、α-生育酚、维生素C、硒和锌浓度之间的关系。关于健康状况、饮酒、吸烟习惯、在SU.VI.MAX研究的1821名年龄在35 - 60岁的女性和1307名年龄在45 - 60岁的男性中获得人体测量数据和生化测量。饮食摄入量的数据是在一个子样本谁报告6个24小时的饮食记录在头18个月的study.Results：妇女有较高的基线血清β-胡萝卜素和维生素C的浓度和较低的浓度血清维生素E，锌和硒比男性。在女性中，年龄较小与血清β-胡萝卜素、维生素E和硒的平均浓度降低有关。在男性中，仅观察到血清锌的差异，老年男性的血清锌较低。目前吸烟的男女血清β-胡萝卜素，维生素C和硒的浓度显着较低，只有在妇女中，维生素E，比不吸烟者。饮酒者血清β-胡萝卜素浓度较低，硒浓度较高。肥胖受试者的血清β-胡萝卜素和维生素C浓度较低。膳食β-胡萝卜素、维生素C和E与其血清浓度呈正相关。年龄、营养和酒精摄入、血清胆固醇、BMI和吸烟状况分别解释了男性和女性血清β-胡萝卜素的15.2%和13.9%、血清维生素C的10.8%和10.0%、血清维生素E的26.3%和28.6%。血清抗氧化营养素浓度主要受性别、年龄、肥胖、吸烟、饮酒，尤其是这些抗氧化营养素的饮食摄入量的影响。
Objective: To assess relationships between energy, nutrient and food intakes, alcohol consumption, smoking status and body mass index (BMI), and serum concentrations of beta-carotene, alpha-tocopherol, vitamin C, selenium and zinc.Methods: Data on health status, alcohol consumption, smoking habits, anthropometric data and biochemical measurements were obtained in 1821 women aged 35 - 60 y and 1307 men aged 45 - 60 y, participant to the SU.VI.MAX Study. Data on dietary intake were available on a subsample who reported six 24-h dietary records during the first 18 months of the study.Results: Women had higher baseline serum beta-carotene and vitamin C concentrations and lower concentration for serum vitamin E, zinc and selenium than men. In women, younger age was associated with lowered mean concentration of serum beta-carotene, vitamin E and selenium. In men, only differences were observed for serum zinc, which was lower in older men. Current smokers of both sexes had significantly lower concentrations of serum beta-carotene, vitamin C and selenium, and, only in women, of vitamin E, than nonsmokers. Alcohol consumers had lower concentrations of serum beta-carotene and higher selenium concentrations. Serum beta-carotene and vitamin C concentrations were lower in obese subjects. There were positive associations of dietary beta-carotene, vitamin C and E with their serum concentrations. Age, nutrient and alcohol intakes, serum cholesterol, BMI and smoking status explained 15.2% of the variance of serum beta-carotene in men and 13.9% in women, and 10.8 and 10.0% for serum vitamin C, and 26.3 and 28.6% for serum vitamin E, respectively.Conclusion: Serum antioxidant nutrient concentrations are primarily influenced by sex, age, obesity, tobacco smoking, alcohol consumption and especially dietary intake of those antioxidant nutrients.