Thickness, taper, and ellipticity in the aortoiliac bifurcation of patients aged 1 day to 76 years
Thickness, taper, and ellipticity in the aortoiliac bifurcation of patients aged 1 day to 76 years
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DOI：
10.1007/bf01744592
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发表时间：
1998-01-01
影响因子：
1.5
通讯作者：
Roach, MR
中科院分区：
文献类型：
--
作者：
MacLean, NF;Roach, MR
对 14 名年龄在 1 天至 76 岁之间的患者尸检时获得的主动脉髂分叉处的管腔面积、椭圆率和壁厚度进行了测量。该方法包括在冷冻切片机的平台上冷冻压力固定的染色分叉，然后在取出切片时观察块面。面积变化根据段长度进行标准化，以产生锥度（变窄，以 mm(2)/mm 为单位）或喇叭口（扩张）值。根据面积变化将主动脉髂分叉分为三个区域：对应于分叉顶点的心尖区域（锥度= 2.96 +/- 0.80 mm(2)/mm）、心尖前区域（喇叭形= 3.58 +/- 0.87 mm（2）/mm）和心尖后区域（喇叭形= 0.82 +/- 0.80毫米（2）/毫米）。心尖前管腔椭圆度显示前后径始终小于侧径，而椭圆度随着年龄的增长而增大。以极坐标评估的平均周向壁厚在 0 度（右侧）和 120 度之间减小，而在 120 度和 200 度之间壁厚显着增加。最显着的差异出现在 1 日龄的婴儿中，其后部非常薄。对主动脉髂分叉的详细几何分析表明，当试图将主动脉中的物理因素与动脉粥样硬化病变和壁重塑的精确位置相关联时，需要考虑锥度、兔形以及周向和纵向壁厚度的变化。
Lumen area, ellipticity, and wall thickness were measured in the aortoiliac bifurcations obtained at autopsy from 14 patients aged between 1 day and 76 years. The method involved freezing pressure-fixed, stained bifurcations on the stage of a refrigerated microtome and then looking at the block face while sections were removed. Area change was normalized over segment length to produce a value of either taper (narrowing, in mm(2)/mm), or flare (expansion). The aortoiliac bifurcations were divided into three regions based on the area changes: an apical region corresponding to the bifurcation apex (taper = 2.96 +/- 0.80 mm(2)/mm), a preapical region (flare = 3.58 +/- 0.87 mm(2)/mm), and the postapical region (flare = 0.82 +/- 0.80 mm(2)/mm). Preapical lumen ellipticity showed that the anterioposterior diameter was always less than the lateral diameter, while the degree of ellipticity increased with age. Average circumferential wall thickness, assessed in polar coordinates, decreased between 0 degrees (right lateral) and 120 degrees, while a significant increase in wall thickness was present between 120 degrees and 200 degrees. The most striking difference was found in the 1-day-old, which was very thin posteriorly. This detailed geometric analysis of the aortoiliac bifurcation suggests that taper, hare, and variations in both circumferential and longitudinal wall thickness need to be considered when trying to correlate physical factors in the aorta with the precise location of atherosclerotic lesions and wall remodeling.