The veno-arteriolar reflex in free skin flaps.

The veno-arteriolar reflex in free skin flaps.
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游离皮瓣中的静脉-小动脉反射。

DOI:
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发表时间:
1989
期刊:
Clinical Physiology
影响因子:
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通讯作者:
E. Tan
E. Tan
中科院分区:
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文献类型:
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作者:
N. Zoltie;C. Young;I. Faris;E. Tan

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我们测量了10名受试者的静脉-小动脉反射,这些受试者在3周至2年前进行了皮肤和皮下组织的自由皮瓣转移后,下肢存在失神经皮肤区域。在皮瓣皮肤、邻近神经支配皮肤和皮瓣皮肤血管化学扩张后,测量血管收缩剂对依赖性的反应。这种静脉-小动脉反射导致血流量减少30-40%,在正常皮肤和去神经皮肤中都是一样的。这种反应被化学血管扩张所消除。结果表明,交感神经支配不是静脉-小动脉反射所必需的,并表明肌生成机制可能比以前认为的更重要。
The veno-arteriolar reflex was measured in 10 subjects in whom an area of denervated skin was present in the lower limb following free flap transfer of skin and subcutaneous tissue 3 weeks to 2 years previously. The vasoconstrictor response to dependency was measured in the skin of the flap, in adjacent innervated skin and after chemical dilatation of cutaneous vessels in the skin of the flap. This veno-arteriolar reflex resulting in a reduction of blood flow of 30-40% was present and equal in both normal and denervated skin. The response was abolished by chemical vasodilatation. The results indicate that sympathetic innervation is not essential for the veno-arteriolar reflex, and suggest that myogenic mechanisms may be more important than previously believed.