Age, sex, material deprivation and respiratory mortality
Age, sex, material deprivation and respiratory mortality
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DOI：
10.1016/j.rmed.2005.10.014
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发表时间：
2006-07-01
影响因子：
4.3
通讯作者：
Hawker, Jeremy I.
中科院分区：
文献类型：
--
作者：
Jordan, Rachel;Verlander, Neville;Hawker, Jeremy I.
本研究的目的是检查年龄、性别和社会剥夺对呼吸道感染死亡率的影响。一项生态研究进行了，使用官方的公共卫生死亡率数据和人口普查数据的西米德兰兹卫生区，英国。死亡时的邮政编码被用来分配汤森剥夺分数和由此产生的剥夺五分位数。Poisson回归分析用于估计呼吸死亡率、剥夺五分位数、年龄和性别之间的关系。在大多数年龄组中，随着贫困程度的增加，死亡率呈显著上升趋势。45-64岁年龄组中最贫困人群的相对风险最高（RR = 4.4，95% CI 4.0，4.8）。然而，75-84岁人群的绝对风险更大（RR = 1.3，95% CI 1.3，1.4），年死亡率为669/100，000。在配偶中观察到一致的较高死亡率。这些结果表明，呼吸道感染的死亡风险因性别而异，一般随着年龄和贫困程度的增加而增加。贫困与呼吸道感染死亡率之间的关联与贫困对许多其他疾病的影响是一致的。解决健康不良的社会决定因素可能有助于减轻英国呼吸道死亡率的高负担。然而，需要进行个人层面的研究和对其他领域的审查，以解释贫困增加呼吸道感染死亡风险的机制，从而确定有效干预的目标群体。(c)2005爱思唯尔有限公司保留所有权利。
The aim of this study was to examine the effects of age, sex and social deprivation on mortality rates for respiratory infection. An ecological study was undertaken, using official public health mortality data and population census data for the West Midlands health region, UK. Postcodes at the time of death were used to assign Townsend deprivation scores and the resulting deprivation quintile. Poisson regression analysis was used to estimate the association between respiratory mortality, deprivation quintile, age and sex. In most age groups there was a statistically significant trend of increasing mortality with increasing deprivation. The relative risk for the most deprived was highest in the 45-64 year age-group (RR = 4.4, 95% CI 4.0, 4.8). However, the absolute risks were greater in those aged 75-84 years (RR = 1.3, 95% CI 1.3, 1.4) where the annual death rate was 669 per 100,000. Consistently higher mortality rates were seen in mates. These results suggest that the risk of mortality from respiratory infection varies by sex and generally increases with increasing age and deprivation quintile. The identified association between deprivation and mortality from respiratory infections is consistent with the effect of deprivation on many other diseases. Addressing the social determinants of ill health may help to reduce the high burden of respiratory mortality in the UK. However, individual level studies and examination of other areas are needed to explain the mechanisms by which deprivation increases the risk of mortality from respiratory infection, and thereby identify target groups for effective interventions. (c) 2005 Elsevier Ltd. All rights reserved.