Sub-wavelength lateral detection of tissue-approximating masses using an ultrasonic metamaterial lens.
Sub-wavelength lateral detection of tissue-approximating masses using an ultrasonic metamaterial lens.
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DOI：
10.1038/s41467-020-19591-2
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发表时间：
2020-11-24
影响因子：
16.6
通讯作者：
Neogi A
中科院分区：
文献类型：
--
作者：
Walker EL;Jin Y;Reyes D;Neogi A
超声生物医学成像的实际应用技术采用延迟求和（DAS）波束形成，其可以在声学菲涅耳区内分辨两个低至2.1λ的物体。在这里，我们展示了一种声子超材料透镜（ML），用于检测发射器的声子晶体消逝区和菲涅尔区之外的组织状体模中的横向亚波长物体特征。ML产生比发射换能器小8倍的超材料准直。利用准直，实现了超过菲涅耳区限制的3.6倍的横向分辨率。在菲涅耳区极限附近的明胶组织模型中检查硬物体和组织近似肿块。对于硬物体，横向尺寸和分离分辨率低至0.50λ，组织近似质量略高，为0.73λ。这项工作代表了超材料的空间特性的应用，并在生物系统的亚波长分辨率超越菲涅尔区的限制。在生物医学应用中，传统的超声检测方法受到有限的横向分辨率的影响。在这里，作者表明，声子超材料透镜可用于亚波长物体的空间表征，甚至超出发射换能器的菲涅尔区。
Practically applied techniques for ultrasonic biomedical imaging employ delay-and-sum (DAS) beamforming which can resolve two objects down to 2.1λ within the acoustic Fresnel zone. Here, we demonstrate a phononic metamaterial lens (ML) for detection of laterally subwavelength object features in tissue-like phantoms beyond the phononic crystal evanescent zone and Fresnel zone of the emitter. The ML produces metamaterial collimation that spreads 8x less than the emitting transducer. Utilizing collimation, 3.6x greater lateral resolution beyond the Fresnel zone limit was achieved. Both hard objects and tissue approximating masses were examined in gelatin tissue phantoms near the Fresnel zone limit. Lateral dimensions and separation were resolved down to 0.50λ for hard objects, with tissue approximating masses slightly higher at 0.73λ. The work represents the application of a metamaterial for spatial characterization, and subwavelength resolution in a biosystem beyond the Fresnel zone limit. Traditional methods for ultrasound detection in biomedical application suffer from limited lateral resolution. Here, the authors show that a phononic metamaterial lens can be used for spatial characterisation of subwavelength objects, even beyond the Fresnel zone of the emitting transducer.
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影响因子：
13.6
作者：
Collins DJ;Devendran C;Ma Z;Ng JW;Neild A;Ai Y
通讯作者：
Ai Y
影响因子：
16.6
作者：
Kurosu M;Hatanaka D;Onomitsu K;Yamaguchi H
通讯作者：
Yamaguchi H
影响因子：
10.6
作者：
Bottenus N;Long W;Zhang HK;Jakovljevic M;Bradway DP;Boctor EM;Trahey GE
通讯作者：
Trahey GE
影响因子：
10.6
作者：
Diamantis, Konstantinos;Anderson, Tom;Sboros, Vassilis
通讯作者：
Sboros, Vassilis
影响因子：
2.4
作者：
Lavarello, Roberto J.;Ghoshal, Goutam;Oelze, Michael L.
通讯作者：
Oelze, Michael L.