Heat stroke.
Heat stroke.
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DOI：
10.1186/s40560-018-0298-4
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发表时间：
2018
影响因子：
7.1
通讯作者：
Miyake Y
中科院分区：
文献类型：
--
作者：
Hifumi T;Kondo Y;Shimizu K;Miyake Y
中暑是一种危及生命的伤害，需要神经重症监护;然而，由于几个可能的原因，中暑尚未得到完全检查，例如没有普遍接受的定义或分类，以及每隔几年就会发生热浪受害者。因此，在这篇综述中，我们阐明了中暑的定义/分类，病理生理学和预后因素，并总结了目前的研究结果，关于中暑的管理，包括使用血管内球囊导管系统，血液净化治疗，连续脑电图监测，抗凝治疗。中暑的定义/分类有两个系统，即Bouchama定义和日本急性医学协会标准。根据对危险因素的详细分析，中暑的预防策略，如使用空调，很重要。此外，入院时血液、心血管、神经和肾功能障碍与高死亡率相关，因此代表了中暑患者强化和特异性治疗的潜在目标。没有前瞻性、可比性研究证实血管内冷却装置、抗凝或血液净化在中暑中的疗效。降温设备、药物和治疗中暑的有效性仍然没有定论。需要进一步的大型研究来继续评估这些治疗策略。
Heat stroke is a life-threatening injury requiring neurocritical care; however, heat stroke has not been completely examined due to several possible reasons, such as no universally accepted definition or classification, and the occurrence of heat wave victims every few years. Thus, in this review, we elucidate the definition/classification, pathophysiology, and prognostic factors related to heat stroke and also summarize the results of current studies regarding the management of heat stroke, including the use of intravascular balloon catheter system, blood purification therapy, continuous electroencephalogram monitoring, and anticoagulation therapy. Two systems for the definition/classification of heat stroke are available, namely Bouchama’s definition and the Japanese Association for Acute Medicine criteria. According to the detailed analysis of risk factors, prevention strategies for heat stroke, such as air conditioner use, are important. Moreover, hematological, cardiovascular, neurological, and renal dysfunctions on admission are associated with high mortality, which thus represent the potential targets for intensive and specific therapies for patients with heat stroke. No prospective, comparable study has confirmed the efficacy of intravascular cooling devices, anticoagulation, or blood purification in heat stroke. The effectiveness of cooling devices, drugs, and therapies in heat stroke remains inconclusive. Further large studies are required to continue to evaluate these treatment strategies.
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影响因子：
38.9
作者：
Hausfater, Pierre;Megarbane, Bruno;Riou, Bruno
通讯作者：
Riou, Bruno
影响因子：
--
作者：
Argaud, Laurent;Ferry, Tristan;Robert, Dominique
通讯作者：
Robert, Dominique
影响因子：
7.5
作者：
Gando, Satoshi;Saitoh, Daizoh;Shimazaki, Shuji
通讯作者：
Shimazaki, Shuji
影响因子：
6.7
作者：
Hagiwara, Satoshi;Iwasaka, Hideo;Noguchi, Takayuki
通讯作者：
Noguchi, Takayuki
影响因子：
8.8
作者：
Diringer, MN
通讯作者：
Diringer, MN