Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)-tricyclohexylphosphine complexes
Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)-tricyclohexylphosphine complexes
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DOI：
10.1016/s0040-4020(01)00998-x
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发表时间：
2001-12-03
期刊：
影响因子：
2.1
通讯作者：
Miyaura, N
中科院分区：
文献类型：
--
作者：
Ishiyama, T;Ishida, K;Miyaura, N
在KOAc(1.5当量)存在下，在80℃的1，4-二氧六环中，双(频那多)二硼与氯代芳烃发生交叉偶联反应生成频那醇芳基硼酸酯。Pd(Dba)(2)/2.4PCy(3)(3-6摩尔%)。与PdCl2(Dppf)在DMSO中催化的反应相比，该催化剂在较温和的条件下也能有效地与芳基溴化物或三氟酸盐进行类似的偶联反应。(C)2001爱思唯尔科学有限公司。保留所有权利。
The cross-coupling reaction of bis-(pinacolato)diboron with chloroarenes to yield pinacol arylboronates was carried out in 1,4-dioxane at 80 degreesC in the presence of KOAc (1.5 equiv.) and Pd(dba)(2)/2.4PCy(3) (3-6 mol%). The catalyst was also effective to carry out analogous coupling with aryl bromides or triflates under milder conditions than those of the previous procedures catalyzed by PdCl2(dppf) in DMSO. (C) 2001 Elsevier Science Ltd. All rights reserved.