A longitudinal study through adolescence to adulthood: the Young Hearts Project, Northern Ireland
A longitudinal study through adolescence to adulthood: the Young Hearts Project, Northern Ireland
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DOI：
10.1038/sj.ph.1900871
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发表时间：
2002-11-01
期刊：
影响因子：
5.2
通讯作者：
Boreham, CA
中科院分区：
文献类型：
--
作者：
Gallagher, AM;Savage, JM;Boreham, CA
“青年之心”项目是一项正在进行的研究，研究来自冠心病死亡率高的北爱尔兰地区的具有代表性的青年样本中心血管疾病的生物和行为风险因素。本文描述了参与该项目的第三阶段（YH3）的个体（年龄在20-25岁）的临床、饮食和生活方式的横断面数据。共有489人（男性251人，女性238人）参与了YH3，应答率为48.2%。约31.1%的YH3参与者超重（BMI bbb25 kg/m(2)）， 4.4%的男性和8.0%的女性肥胖（BMI bbb30 kg/m(2)）。女性比男性的健康状况差（55.0比22.1%，卡方51.70,d.f 1, P < 0.001），并且没有参加任何体育或锻炼活动（38.4比24.9%，卡方10.26,d.f 1, P = 0.001）。超过20%的参与者血清总胆固醇升高（>5.2 mmol/l）。血清ldl -胆固醇升高（>3.0 mmol/l）女性高于男性（44.6% vs 34.6%，卡方4.39,χ 2 = 1, P < 0.05）。超过46%的参与者报告从脂肪中摄取的能量高于建议水平，68.5%的参与者的饱和脂肪摄入量高于建议水平。(英国食物能量和营养的膳食参考值。生物医学工程学报，1999)。超过一半的研究对象报告说，他们的酒精摄入量超过了英国皇家医师学会（Royal College of Physicians）建议的合理限度（一个日益严重的邪恶：酒精滥用的医学后果）。Tavistock: London, 1987)，其中36.7%的男性和13.4%的女性报告摄入量超过了推荐限量的两倍。研究人群中有37%的人吸烟。在青年时期，个体可能不太愿意参加与健康相关的研究，并且在研究的当前阶段招募参与者被证明是一个主要问题。然而，这些数据构成了北爱尔兰队列中从青春期到青年期的独特发展记录，并提供了关于早期生活、童年和青年期对慢性疾病风险发展的影响的额外信息。
The Young Hearts (YH) Project is an ongoing study of biological and behavioural risk factors for cardiovascular disease in a representative sample of young people from Northern Ireland, a region of high coronary mortality. This article describes the cross-sectional clinical, dietary and lifestyle data obtained from individuals (aged 20-25 y) who participated in phase 3 of the project (YH3). A total of 489 individuals (251 males, 238 females) participated in YH3 (48.2% response rate). Some 31.1 % of participants at YH3 were overweight (BMI > 25 kg/m(2)) with 4.4% of males and 8.0% of females were obese (BMI > 30 kg/m(2)). More females than males had a very poor fitness (55.0 vs 22.1%, chi-squared 51.70, d.f. 1, P < 0.001) and did not participate in any sporting or exercise activity (38.4 vs 24.9%, chi-squared 10.26, d.f. 1, P = 0.001). Over 20% of participants had a raised total serum cholesterol (>5.2 mmol/l). More females had a raised serum LDL-cholesterol (>3.0 mmol/l) than males (44.6 vs 34.6%, chi-squared 4.39, d.f 1, P < 0.05). Over 46% of participants reported energy intakes from fat above recommended levels, and 68.5% of participants had saturated fat intakes above those recommended. (Dietary reference values for food energy and nutrients for the United Kingdom. HMSO: London, 199 1). Just over half of the study population reported alcohol intakes in excess of recommended sensible limits set by the Royal College of Physicians (A great and growing evil: the medical consequences of alcohol abuse. Tavistock: London, 1987), with 36.7% of males and 13.4% of females reporting intakes over twice these recommended limits. A total of 37% of the study population smoked. During young adulthood, individuals may be less amenable to attend a health-related study and recruitment of participants to the current phase of the study proved a major problem. However, these data constitute a unique developmental record from adolescence to young adulthood in a cohort from Northern Ireland and provide additional information on the impact of early life, childhood and young adulthood on the development of risk for chronic disease.