Growth Comparison in Children with and without Food Allergies in 2 Different Demographic Populations
Growth Comparison in Children with and without Food Allergies in 2 Different Demographic Populations
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DOI：
10.1016/j.jpeds.2014.06.003
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发表时间：
2014-10-01
影响因子：
5.1
通讯作者：
Wang, Julie
中科院分区：
文献类型：
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作者：
Mehta, Harshna;Ramesh, Manish;Wang, Julie
目的探讨食物回避对食物过敏儿童生长发育的影响。研究设计：对2个纽约市普通儿科诊所的食物过敏儿童和非食物过敏儿童进行回顾性图表回顾。根据国际疾病分类第9次修订版中的代码选择健康儿童访视、食物过敏、速发过敏反应和/或肾上腺素自动注射器处方的图表。身高和体重计算体重指数，身高，体重z-scores.Results的9938名儿童看到，439（4.4%）避免一种或多种食物。在那些有商业保险的儿童中，有食物过敏的儿童比没有食物过敏的儿童（平均身高z分数= 0.42;平均体重z分数= 0.07）明显更矮（平均身高z分数= 0.06; P = 0.01）和更轻（平均体重z分数-0.1; P = 0.006）。相比之下，有食物过敏且有国家保险的儿童的身高或体重并不比没有食物过敏的儿童低。在白色受试者中，食物过敏对身高和体重有显著影响（身高P = 0.012，体重P = 0.0036），而西班牙裔/拉丁裔、黑人或亚洲受试者中未观察到这种影响。牛奶过敏的儿童体重显着低于没有牛奶过敏的儿童（P =.0006）。结论与那些没有食物过敏的儿童相比，食物过敏和商业保险有显着损害的增长。此外，不喝任何形式牛奶的儿童比同龄人更矮，体重更轻。因此，对食物过敏的儿童应定期进行身高和体重测量，因为这一人群存在生长障碍的风险。
Objective To examine the effects of food avoidance on the growth of children with food allergies.Study design A retrospective chart review was performed for children with and without food allergies followed at 2 New York City general pediatric practices. Charts were selected based on codes from the International Classification of Diseases, 9th Revision, for well child visit, food allergy, anaphylaxis, and/or epinephrine autoinjector prescriptions. Heights and weights were obtained to calculate body mass index, height, and weight z-scores.Results Of the 9938 children seen, 439 (4.4%) were avoiding one or more foods. Of those with commercial insurance, children with food allergies were significantly shorter (mean height z-score = 0.06; P = .01) and weighed less (mean weight z-score -0.1; P = .006) than children without food allergies (mean height z-score = 0.42; mean weight z-score = 0.07). In contrast, children with food allergies and state insurance were not smaller in height or weight compared with children without food allergies. Among white subjects, there was a significant effect of food allergies on height and weight (ANOVA for height P = .012, for weight P = .0036) that was not observed for Hispanic/Latino, black, or Asian subjects. Children with allergies to milk weighed significantly less than children without milk allergies (P = .0006).Conclusions Children with food allergies and commercial insurance have significant impairment in growth compared with those without food allergies. Additionally, children avoiding all forms of milk are shorter and weigh less than matched counterparts. Therefore, height and weight measurements should be assessed routinely in children with food allergies because there is risk for growth impairment in this population.