Effects of restricted daily feeding on neuropeptide Y release in the rat paraventricular nucleus.
Effects of restricted daily feeding on neuropeptide Y release in the rat paraventricular nucleus.
复制标题
限制每日进食对大鼠室旁核神经肽 Y 释放的影响。
DOI：
10.1152/ajpendo.1996.270.4.e589
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
K. Honma
中科院分区：
文献类型：
--
作者：
T. Yoshihara;S. Honma;K. Honma
在固定时间进食和随意进食两种情况下，测定了大鼠室旁核（PVN）附近的细胞外神经肽Y (NPY)，以及PVN、下丘脑弓状核（ARC）和孤束核（NTS）中的细胞外神经肽Y浓度。在0600和2200之间，自由喂养大鼠的细胞外NPY水平没有显著变化，但在进食前增加，在平均供应后立即下降。同样，PVN、ARC和NTS中的NPY浓度在餐前立即升高。在正常用餐时间不进食时，细胞外NPY水平没有迅速下降，PVN内NPY浓度保持在较低水平。大鼠在RF终止后进行喂养-禁食模式。在饲喂期间，细胞外NPY水平恢复到基础水平，但在禁食期间，NPY水平升高的时间几乎与RF方案下的供餐时间相同。综上所述，RF方案下PVN中NPY释放的预摄食增强受摄食相关昼夜节律的调节。
Extracellular neuropeptide Y (NPY) in the vicinity of the paraventricular nucleus (PVN) and the NPY concentrations in the PVN, arcuate nucleus of the hypothalamus (ARC), and the nucleus tractus solitarius (NTS) were measured in rats under ad libitum and restricted daily feeding (RF) where meal was supplied at a fixed time of day. The extracellular NPY levels did not vary significantly between 0600 and 2200 in rats under ad libitum feeding but were increased before meal and decreased immediately after mean supply under the RF regimen. Similarly, the NPY concentrations in the PVN, ARC, and NTS were increased immediately before meal. When meal was omitted at the regular mealtime, the extracellular NPY levels were not decreased rapidly, and the NPY concentration in the PVN remained at a low level. Rats were subjected to the feeding-fasting paradigm after the termination of RF. The extracellular NPY levels were returned to basal levels during the feeding period but were elevated during the fasting period at almost the same time as that for meal supply under the RF regimen. It is concluded that the prefeeding enhancement of the NPY release in the PVN under the RF regimen is regulated by the feeding-associated circadian rhythm.
神经肽 Y 影响卵巢切除大鼠黄体生成素和生长激素的分泌。
DOI：
10.1073/pnas.82.2.561
发表时间：
1985
影响因子：
11.1
作者：
McDonald,JK;Lumpkin,MD;Samson,WK;McCann,SM
通讯作者：
McCann,SM
DOI：
10.1073/pnas.88.23.10931
发表时间：
1991-12-01
影响因子：
11.1
作者：
KALRA, SP;DUBE, MG;KALRA, PS
通讯作者：
KALRA, PS
预定喂养方案大鼠下丘脑神经肽 Y 基因的表达。
DOI：
10.1016/0169-328x(92)90145-2
发表时间：
1992
期刊：
Brain research. Molecular brain research
影响因子：
--
作者：
Sahu,A;White,JD;Kalra,PS;Kalra,SP
通讯作者：
Kalra,SP