Ruptured Cerebral Aneurysm and Acute Coronary Artery Dissection in the Setting of Multivascular Fibromuscular Dysplasia
Ruptured Cerebral Aneurysm and Acute Coronary Artery Dissection in the Setting of Multivascular Fibromuscular Dysplasia
复制标题
多血管纤维肌性发育不良背景下的脑动脉瘤破裂和急性冠状动脉夹层
作者：
S. Brodsky;G. Ramaswamy;P. Chander;A. Braun
纤维肌肉发育不良（FMD）是一种节段性非炎症性非动脉粥样硬化性血管疾病，几乎在所有动脉床中都有报道，包括大脑和冠状动脉。脑血管FMD与受累血管中囊状动脉瘤的发生有关。急性冠状动脉夹层也是FMD罕见的并发症。在此，我们报告第一例同时出现FMD两种并发症的病例——前交通动脉瘤破裂和右冠状动脉夹层，发生在一名38岁的女性身上。尸检时，在多个血管床上发现口蹄疫。我们的研究结果揭示了口蹄疫患者可能涉及多个血管床，导致多种血管并发症。
Fibromuscular dysplasia (FMD) is a segmental noninflammatory nonatherosclerotic vascular disease that has been described in almost every arterial bed, including the cerebral and coronary arteries. FMD of cerebral vessels has been associated with development of saccular aneurysms in the involved vessels. Acute dissection of coronary arteries is also a rare complication of FMD. Herein, we report the first case of both complications of FMD occurring in a single patient—a ruptured anterior communicating artery aneurysm and a right coronary artery dissection occurring in a 38-year-old woman. At autopsy, FMD was found in multiple vascular beds. Our findings reveal the potential for involvement of several vascular beds in patients with FMD, resulting in multiple vascular complications.