Vagal Recovery From Cognitive Challenge Moderates Age-Related Deficits in Executive Functioning.
Vagal Recovery From Cognitive Challenge Moderates Age-Related Deficits in Executive Functioning.
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DOI：
10.1177/0164027515593345
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发表时间：
2016-05
影响因子：
2.6
通讯作者：
Sloan RP
中科院分区：
文献类型：
--
作者：
Crowley OV;Kimhy D;McKinley PS;Burg MM;Schwartz JE;Lachman ME;Tun PA;Ryff CD;Seeman TE;Sloan RP
执行功能（EF）下降是认知老化的标志。我们以前曾报道过，迷走神经从认知挑战中恢复得更快与更好的EF相关。这项研究在美国中年研究（35-86岁）的817名参与者中检查了迷走神经从认知挑战中恢复与EF年龄相关差异之间的关系。心脏迷走神经控制以高频心率变异性测量。迷走神经恢复调节了年龄与EF之间的相关性（β = .811，p = .004）。二次分析显示，迷走神经恢复较快的老年参与者（65-86岁）与迷走神经恢复较慢的同龄人相比具有更上级的EF。相反，在年轻（35-54岁）和中年（55-64岁）参与者中，迷走神经恢复与EF无关。我们的结论是，更快的迷走神经从认知挑战中恢复与老年人EF缺陷的减少有关，但与年轻人无关。
Decline in executive functioning (EF) is a hallmark of cognitive aging. We have previously reported that faster vagal recovery from cognitive challenge is associated with better EF. This study examined the association between vagal recovery from cognitive challenge and age-related differences in EF among 817 participants in the Midlife in the U.S. study (aged 35–86). Cardiac vagal control was measured as high-frequency heart rate variability. Vagal recovery moderated the association between age and EF (β = .811, p = .004). Secondary analyses revealed that older participants (aged 65–86) with faster vagal recovery had superior EF compared to their peers who had slower vagal recovery. In contrast, among younger (aged 35–54) and middle-aged (aged 55–64) participants, vagal recovery was not associated with EF. We conclude that faster vagal recovery from cognitive challenge is associated with reduced deficits in EF among older, but not younger individuals.