Tea catechin supplementation increases antioxidant capacity and prevents phospholipid hydroperoxidation in plasma of humans.

Tea catechin supplementation increases antioxidant capacity and prevents phospholipid hydroperoxidation in plasma of humans.
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茶儿茶素补充剂可提高抗氧化能力并防止人体血浆中磷脂氢过氧化。

DOI:
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发表时间:
1999
影响因子:
6.1
通讯作者:
T. Miyazawa
T. Miyazawa
中科院分区:
农林科学1区
文献类型:
--
作者:
K. Nakagawa;Manabu Ninomiya;Tsutomu Okubo;N. Aoi;L. Juneja;Mujo Kim;Kenji Yamanaka;T. Miyazawa

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研究了绿茶儿茶素补充剂对人血浆抗氧化能力的影响。口服绿茶提取物(254 毫克总儿茶素/受试者)的 18 名健康男性志愿者在给药后 60 分钟显示每毫升血浆中含有 267 pmol 表没食子儿茶素-3-没食子酸酯 (EGCg)。儿茶素治疗受试者的血浆磷脂酰胆碱过氧化氢 (PCOOH) 水平从对照组的 73.7 pmol/mL 降至 44.6 pmol/mL,与血浆 EGCg 水平的增加呈反比。结果表明,喝绿茶有助于通过提高人体血浆抗氧化能力来预防心血管疾病。
The effect of green tea catechin supplementation on antioxidant capacity of human plasma was investigated. Eighteen healthy male volunteers who orally ingested green tea extract (254 mg of total catechins/subject) showed 267 pmol of epigallocatechin-3-gallate (EGCg) per milliliter of plasma at 60 min after administration. The plasma phosphatidylcholine hydroperoxide (PCOOH) levels attenuated from 73.7 pmol/mL in the control to 44.6 pmol/mL in catechin-treated subjects, being correlated inversely with the increase in plasma EGCg level. The results suggested that drinking green tea contributes to prevent cardiovascular disease by increasing plasma antioxidant capacity in humans.