Early childhood sleep and eating problems as predictors of adolescent and adult mood and anxiety disorders
Early childhood sleep and eating problems as predictors of adolescent and adult mood and anxiety disorders
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DOI：
10.1016/j.jad.2006.05.025
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发表时间：
2006-11-01
影响因子：
6.6
通讯作者：
Weissman, Myrna M.
中科院分区：
文献类型：
--
作者：
Ong, Say How;Wickramaratne, Priya;Weissman, Myrna M.
背景资料：最近的研究表明，儿童早期的饮食和睡眠问题可能是晚年情绪和焦虑症的危险因素。我们的目的是研究儿童早期的睡眠和饮食问题，特别是高运动活动在睡眠和睡眠/饮食时间表的不规则性，和一生的历史情绪和焦虑disorders.Methods：我们随访了164个后代，谁是在高和低风险的抑郁症凭借他们的父母的历史（至少有一个父母有严重的抑郁症）之间的关联。目标睡眠和饮食问题进行了测量气质调查（DOTS）的维度。在20年内使用结构化诊断访谈对后代进行了3次盲法评估。结果：儿童期睡眠和饮食时间不规律（低节律性）与青少年期发作的重度抑郁症和焦虑症以及儿童期发作的焦虑症有关。睡眠中的高运动活动水平与儿童期发作和成年期发作的心境恶劣障碍有关。儿童期睡眠和饮食不规律与成人发病psychopathology.Limitations：回顾性报告的儿童期睡眠和饮食模式来自父母的报告。报告的问题可能与临床diagnosis.Conclusion重叠：临床医生应警惕父母报告的儿童的睡眠和饮食问题，这表明低节奏，以及高运动活动水平在睡眠期间。这些早期行为可能预示着儿童和青少年随后的情绪和焦虑障碍。(c)2006 Elsevier B. V.保留所有权利。
Background: Recent studies have suggested that eating and sleep problems during early childhood may pose as risk factors for mood and anxiety disorders in later life. We aim to study the associations between early childhood sleep and eating problems, specifically high motor activity during sleep and irregularities in sleep/eating schedules, and lifetime history of mood and anxiety disorders.Methods: We followed up 164 offspring, who were at high and low risk for major depression by virtue of their parental history (at least one parent had Major Depressive Disorder). Target sleep and eating problems were measured using Dimensions of Temperament Survey (DOTS). The offspring were blindly assessed at 3 times over 20 years using a structured diagnostic interview.Result: Irregularities in sleeping and eating schedules in childhood (low rhythmicity) was associated with adolescent-onset major depression and anxiety disorder, as well as childhood-onset anxiety disorder. High motor activity level during sleep was associated with both childhood-onset and adolescent-onset dysthymic disorder. Neither childhood sleep nor eating irregularities were associated with adult onset psychopathology.Limitations: Retrospective reports of childhood sleep and eating patterns were derived from parent-reports. Reported problems may overlap with clinical diagnoses.Conclusion: Clinicians should be alerted to parental reports of children's sleep and eating problems suggesting low rhythmicity, as well as high motor activity levels during sleep. These early behaviors may be predictive of subsequent mood and anxiety disorders in childhood and adolescence. (c) 2006 Elsevier B.V. All rights reserved.